Literature DB >> 2998886

Reduction in the stearic to oleic acid ratio in human malignant liver neoplasms.

C B Wood, N A Habib, K Apostolov, A Thompson, W Barker, M Hershman, L H Blumgart.   

Abstract

Total lipid extracts of liver tissue from 14 patients with primary and secondary liver tumours were analysed for relative values of saturation of 18 carbon chain length fatty acids (C18FA). The saturation indices (ratio C18S:C18u) of the tumour areas were significantly and consistently lower than the corresponding values in the non-tumour areas (P less than 0.001). It is proposed that the relative increase in unsaturated C18FA (oleic acid) could prove to be a chemical marker reflecting deficient cellular control of the desaturation of stearic acid.

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Year:  1985        PMID： 2998886

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN： 0748-7983            Impact factor:   4.424


  10 in total

1.  Incorporation and metabolic conversion of saturated and unsaturated fatty acids in SK-Hep1 human hepatoma cells in culture.

Authors:  C A Marra; M J de Alaniz
Journal:  Mol Cell Biochem       Date:  1992-11-18       Impact factor: 3.396

2.  Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas.

Authors:  Yasuo Horie; Akira Suzuki; Ei Kataoka; Takehiko Sasaki; Koichi Hamada; Junko Sasaki; Katsunori Mizuno; Go Hasegawa; Hiroyuki Kishimoto; Masahiro Iizuka; Makoto Naito; Katsuhiko Enomoto; Sumio Watanabe; Tak Wah Mak; Toru Nakano
Journal:  J Clin Invest       Date:  2004-06       Impact factor: 14.808

3.  Increased erythrocyte stearic acid desaturation in rats with chemically induced colorectal carcinomas.

Authors:  N A Habib; M J Hershman; R Salem; W Barker; K Apostolov; C B Wood
Journal:  Int J Colorectal Dis       Date:  1987-02       Impact factor: 2.571

4.  Association of the gene encoding stearoyl-CoA desaturase (SCD) with fatty acid composition in an intercross population between Landrace and Korean native pigs.

Authors:  Dyah Maharani; Hee-Bok Park; Jae-Bong Lee; Chae-Kyoung Yoo; Hyun-Tae Lim; Sang-Hyun Han; Sung-Soo Lee; Moon-Suck Ko; In-Cheol Cho; Jun-Heon Lee
Journal:  Mol Biol Rep       Date:  2012-11-03       Impact factor: 2.316

5.  Effects of high corn oil diet on preneoplastic murine colons: prostanoid production and lipid composition.

Authors:  N M Robblee; R P Bird
Journal:  Lipids       Date:  1994-01       Impact factor: 1.880

6.  Third meeting of the British Oncological Association. York, 3-5 July, 1988. Abstracts.

Authors: 
Journal:  Br J Cancer       Date:  1988-10       Impact factor: 7.640

7.  Fatty acid elongation in non-alcoholic steatohepatitis and hepatocellular carcinoma.

Authors:  Sonja M Kessler; Yvette Simon; Katja Gemperlein; Kathrin Gianmoena; Cristina Cadenas; Vincent Zimmer; Juliane Pokorny; Ahmad Barghash; Volkhard Helms; Nico van Rooijen; Rainer M Bohle; Frank Lammert; Jan G Hengstler; Rolf Mueller; Johannes Haybaeck; Alexandra K Kiemer
Journal:  Int J Mol Sci       Date:  2014-04-04       Impact factor: 5.923

Review 8.  Influence of liver cancer on lipid and lipoprotein metabolism.

Authors:  Jingting Jiang; Peter Nilsson-Ehle; Ning Xu
Journal:  Lipids Health Dis       Date:  2006-03-03       Impact factor: 3.876

9.  Manipulation of body fat composition with sterculic acid can inhibit mammary carcinomas in vivo.

Authors:  D E Khoo; B Fermor; J Miller; C B Wood; K Apostolov; W Barker; R C Williamson; N A Habib
Journal:  Br J Cancer       Date:  1991-01       Impact factor: 7.640

10.  Stearic acid and carcinogenesis.

Authors:  N A Habib; C B Wood; K Apostolov; W Barker; M J Hershman; M Aslam; D Heinemann; B Fermor; R C Williamson; W E Jenkins
Journal:  Br J Cancer       Date:  1987-10       Impact factor: 7.640
  10 in total

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