Literature DB >> 2998861

The effect of sulfhydryl compounds on the catalytic activity of Cu, Zn-superoxide dismutase purified from rat liver.

T Hoshino, Y Ohta, I Ishiguro.   

Abstract

Sulfhydryl compounds such as reduced glutathione, cysteine and 2-mercaptopropionylglycine, a hepato-protective agent, activated Cu, Zn-superoxide dismutase purified from rat liver at low concentrations (below 10 microM). Furthermore we found evidence indicating that this activation is achieved by reducing Cu2+ present in the catalytic site of the dismutase, and thereby promoting the dismutation of superoxide anions.

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Year:  1985        PMID： 2998861     DOI： 10.1007/bf01950012

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

Review 1.  Superoxide dismutases.

Authors:  I Fridovich
Journal:  Annu Rev Biochem       Date:  1975       Impact factor: 23.643

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  The interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide: inactivation of the enzyme.

Authors:  E K Hodgson; I Fridovich
Journal:  Biochemistry       Date:  1975-12-02       Impact factor: 3.162

4.  Isolation and properties of protein component as activator for anthranilamide hydroxylation in rat liver.

Authors:  I Ishiguro; J Naito; R Shinohara; A Ishikura; T Terai
Journal:  Biochim Biophys Acta       Date:  1974-09-13

5.  Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein).

Authors:  J M McCord; I Fridovich
Journal:  J Biol Chem       Date:  1969-11-25       Impact factor: 5.157

6.  A relationship between thiols and the superoxide ion.

Authors:  C J McNeil; J C Banford; D H Brown; W E Smith
Journal:  FEBS Lett       Date:  1981-10-12       Impact factor: 4.124

7.  Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase.

Authors:  S Marklund; G Marklund
Journal:  Eur J Biochem       Date:  1974-09-16

8.  Reaction of copper-zinc superoxide dismutase with diethyldithiocarbamate.

Authors:  H P Misra
Journal:  J Biol Chem       Date:  1979-11-25       Impact factor: 5.157

9.  Re-examination of the reaction of diethyldithiocarbamate with the copper of superoxide dismutase.

Authors:  D Cocco; L Calabrese; A Rigo; E Argese; G Rotilio
Journal:  J Biol Chem       Date:  1981-09-10       Impact factor: 5.157
  9 in total

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