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Literature DB >> 2998860

Benzamide potentiation of behavioral apomorphine-induced effects; mechanism involved.

Abstract

A new N-pyridinyl benzamide was found to potentiate strongly the effects of apomorphine on the motility of reserpinized mice and on circling behavior. Since dopaminergic agonist activity could not account for this potentiation, involvement of alpha 2-adrenergic agonist activity provided the only consistent explanation.

Entities: Chemical Species

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Year: 1985 PMID： 2998860 DOI： 10.1007/bf01950008

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

12 in total

1. Dopamine and noradrenaline receptor stimulation: reversal of reserpine-induced suppression of motor activity.

Authors: N E Andén; U Strömbom; T H Svensson
Journal: Psychopharmacologia Date: 1973

Review 2. Yohimbine: a pharmacological probe for study of the alpha 2-adrenoreceptor.

Authors: M R Goldberg; D Robertson
Journal: Pharmacol Rev Date: 1983-09 Impact factor: 25.468

Review 3. Turning behaviour in animals.

Authors: C J Pycock
Journal: Neuroscience Date: 1980 Impact factor: 3.590

4. Pharmacological properties of new antipsychotic agents: use of animal models.

Authors: A J Puech; P Rioux; M Poncelet; D Brochet; R Chermat; P Simon
Journal: Neuropharmacology Date: 1981-12 Impact factor: 5.250

5. Biochemical and behavioural effects of tyrosine hydroxylase inhibition.

Authors: L C Hanson
Journal: Psychopharmacologia Date: 1967

6. Turning behavior of mice with unilateral 6-hydroxydopamine lesions in the striatum: effects of apomorphine, L-DOPA, amanthadine, amphetamine and other psychomotor stimulants.

Authors: P F Von Voigtlander; K E Moore
Journal: Neuropharmacology Date: 1973-05 Impact factor: 5.250

Benzamide potentiation of behavioral apomorphine-induced effects; mechanism involved.

1. Dopamine and noradrenaline receptor stimulation: reversal of reserpine-induced suppression of motor activity.

Review 2. Yohimbine: a pharmacological probe for study of the alpha 2-adrenoreceptor.

Review 3. Turning behaviour in animals.

4. Pharmacological properties of new antipsychotic agents: use of animal models.

5. Biochemical and behavioural effects of tyrosine hydroxylase inhibition.

6. Turning behavior of mice with unilateral 6-hydroxydopamine lesions in the striatum: effects of apomorphine, L-DOPA, amanthadine, amphetamine and other psychomotor stimulants.

7. Catecholamine receptor agonists: effects on motor activity and rate of tyrosine hydroxylation in mouse brain.

8. Clonidine analgesia: tolerance and cross-tolerance to autoanalgesia.

9. Postsynaptic dopamine agonist properties of TL-99 are revealed by yohimbine co-treatment.

10. The interaction of clonidine with dopamine-dependent behaviour in rodents.

1. Newly discovered anti-inflammatory properties of the benzamides and nicotinamides.

2. Effect of clonidine on experimental brain edema in the rat.