Literature DB >> 29987782

Isolation and Characterization of Mouse Fibroblasts.

Benjamin L Edelman1, Elizabeth F Redente2,3,4.   

Abstract

The lung parenchyma is comprised of many cells including the structurally important stromal fibroblasts. Fibroblasts function to produce extracellular matrix and are important in the maintenance of alveolar epithelial cells. To understand the role of fibroblasts both in homeostasis and disease, we isolate fibroblasts and grow them in culture. Two methods are presented here for the isolation and maintenance of mouse primary lung fibroblasts.

Entities:  

Keywords:  Cell culture; Isolation; Lung digestion; Pulmonary fibroblasts

Mesh：

Substances：

Year:  2018        PMID： 29987782     DOI： 10.1007/978-1-4939-8570-8_5

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  8 in total

1.  Type I Interferon Signaling Increases Versican Expression and Synthesis in Lung Stromal Cells During Influenza Infection.

Authors:  Jourdan E Brune; Mary Y Chang; William A Altemeier; Charles W Frevert
Journal:  J Histochem Cytochem       Date:  2021-10-19       Impact factor: 2.479

2.  Mouse Mx1 Inhibits Herpes Simplex Virus Type 1 Genomic Replication and Late Gene Expression In Vitro and Prevents Lesion Formation in the Mouse Zosteriform Model.

Authors:  Melkamu B Tessema; Rubaiyea Farrukee; Christopher E Andoniou; Mariapia A Degli-Esposti; Clare V Oates; James B Barnes; Linda M Wakim; Andrew G Brooks; Sarah L Londrigan; Patrick C Reading
Journal:  J Virol       Date:  2022-05-31       Impact factor: 6.549

3.  Lack of bombesin receptor-activated protein attenuates bleomycin-induced pulmonary fibrosis in mice.

Authors:  Hui Wang; Wenrui Zhang; Rujiao Liu; Jiaoyun Zheng; Xueping Yao; Hui Chen; Jie Wang; Horst Christian Weber; Xiaoqun Qin; Yang Xiang; Chi Liu; Huijun Liu; Lang Pan; Xiangping Qu
Journal:  Life Sci Alliance       Date:  2022-07-12

4.  Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1.

Authors:  Hongbing Jiang; Christian Leung; Stephen Tahan; David Wang
Journal:  Elife       Date:  2019-11-26       Impact factor: 8.140

5.  Loss of Fas signaling in fibroblasts impairs homeostatic fibrosis resolution and promotes persistent pulmonary fibrosis.

Authors:  Elizabeth F Redente; Sangeeta Chakraborty; Satria Sajuthi; Bart P Black; Ben L Edelman; Max A Seibold; David Wh Riches
Journal:  JCI Insight       Date:  2020-12-08

6.  Elevated NSD3 histone methylation activity drives squamous cell lung cancer.

Authors:  Gang Yuan; Natasha M Flores; Simone Hausmann; Shane M Lofgren; Vladlena Kharchenko; Maria Angulo-Ibanez; Deepanwita Sengupta; Xiaoyin Lu; Iwona Czaban; Dulat Azhibek; Silvestre Vicent; Wolfgang Fischle; Mariusz Jaremko; Bingliang Fang; Ignacio I Wistuba; Katrin F Chua; Jack A Roth; John D Minna; Ning-Yi Shao; Łukasz Jaremko; Pawel K Mazur; Or Gozani
Journal:  Nature       Date:  2021-02-03       Impact factor: 69.504

7.  Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-β/Smad Pathway.

Authors:  Yu Wang; Sibo Sun; Kai Wang; Mingjiong Zhang; Min Li; Yumin Zan; Qiqing Huang; Shuangshuang Wu; Weihong Zhao; Wei Xu; Jianqing Wu
Journal:  Mediators Inflamm       Date:  2022-03-03       Impact factor: 4.711

8.  Expression of a Functional Mx1 Protein Is Essential for the Ability of RIG-I Agonist Prophylaxis to Provide Potent and Long-Lasting Protection in a Mouse Model of Influenza A Virus Infection.

Authors:  Lara S U Schwab; Fernando Villalón-Letelier; Melkamu B Tessema; Sarah L Londrigan; Andrew G Brooks; Aeron Hurt; Christoph Coch; Thomas Zillinger; Gunther Hartmann; Patrick C Reading
Journal:  Viruses       Date:  2022-07-15       Impact factor: 5.818
  8 in total

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