Literature DB >> 29987562

Does obesity impact postoperative outcomes following robotic-assisted surgery for rectal cancer?

E Duchalais1, N Machairas1, S R Kelley1, R G Landmann2, A Merchea2, D T Colibaseanu2, K L Mathis1, E J Dozois1, D W Larson3.   

Abstract

INTRODUCTION: Obesity has been identified as a risk factor for both conversion and severe postoperative morbidity in patients undergoing laparoscopic rectal resection. Robotic-assisted surgery (RAS) is proposed to overcome some of the technical limitations associated with laparoscopic surgery for rectal cancer. The aim of our study was to determine if obesity remains a risk factor for severe morbidity in patients undergoing robotic-assisted rectal resection. PATIENTS: This study was a retrospective review of a prospective database. A total of 183 patients undergoing restorative RAS for rectal cancer between 2007 and 2016 were divided into 2 groups: control (BMI < 30 kg/m2; n = 125) and obese (BMI ≥ 30 kg/m2; n = 58). Clinicopathologic data, 30-day postoperative morbidity, and perioperative outcomes were compared between groups. The main outcome was severe postoperative morbidity defined as any complication graded Clavien-Dindo ≥ 3.
RESULTS: Control and obese groups had similar clinicopathologic characteristics. Severe complications were observed in 9 (7%) and 4 (7%) patients, respectively (p > 0.99). Obesity did not impact conversion, anastomotic leak rate, length of stay, or readmission but was significantly associated with increased postoperative morbidity (29 vs. 45%; p = 0.04) and especially more postoperative ileus (11 vs. 26%; p = 0.01). Obesity and male gender were the two independent risk factors for postoperative overall morbidity (OR 1.97; 95% CI 1.02-3.94; p = 0.04 and OR 2.23; 95% CI 1.10-4.76; p = 0.03, respectively).
CONCLUSION:Obesity did not impact severe morbidity or conversion rate following RAS for rectal cancer but remained a risk factor for overall morbidity and especially postoperative ileus.

Entities:  

Keywords:  Obesity; Postoperative ileus; Postoperative morbidity; Rectal cancer; Rectal resection; Robotic-assisted surgery

Mesh:

Year:  2018        PMID: 29987562     DOI: 10.1007/s00464-018-6247-4

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  31 in total

Review 1.  Outcome of laparoscopic colorectal surgery in obese and nonobese patients: a meta-analysis.

Authors:  Yanming Zhou; Lupeng Wu; Xiudong Li; Xiurong Wu; Bin Li
Journal:  Surg Endosc       Date:  2011-10-20       Impact factor: 4.584

2.  Prolonged high fat diet ingestion, obesity, and type 2 diabetes symptoms correlate with phenotypic plasticity in myenteric neurons and nerve damage in the mouse duodenum.

Authors:  Chloe M Stenkamp-Strahm; Yvonne E A Nyavor; Adam J Kappmeyer; Sarah Horton; Martin Gericke; Onesmo B Balemba
Journal:  Cell Tissue Res       Date:  2015-02-28       Impact factor: 5.249

3.  A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer.

Authors:  H Jaap Bonjer; Charlotte L Deijen; Eva Haglind
Journal:  N Engl J Med       Date:  2015-07-09       Impact factor: 91.245

4.  Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial.

Authors:  Ruben Veldkamp; Esther Kuhry; Wim C J Hop; J Jeekel; G Kazemier; H Jaap Bonjer; Eva Haglind; Lars Påhlman; Miguel A Cuesta; Simon Msika; Mario Morino; Antonio M Lacy
Journal:  Lancet Oncol       Date:  2005-07       Impact factor: 41.316

5.  Robotic versus conventional laparoscopic rectal cancer surgery in obese patients.

Authors:  E Gorgun; V Ozben; M Costedio; L Stocchi; M Kalady; F Remzi
Journal:  Colorectal Dis       Date:  2016-11       Impact factor: 3.788

6.  Robot-assisted versus laparoscopic surgery for lower rectal cancer: the impact of visceral obesity on surgical outcomes.

Authors:  Akio Shiomi; Yusuke Kinugasa; Tomohiro Yamaguchi; Hiroyasu Kagawa; Yushi Yamakawa
Journal:  Int J Colorectal Dis       Date:  2016-09-06       Impact factor: 2.571

7.  Robot-assisted versus conventional laparoscopic surgery for colorectal disease, focusing on rectal cancer: a meta-analysis.

Authors:  Yongzhi Yang; Feng Wang; Peng Zhang; Chenzhang Shi; Yang Zou; Huanlong Qin; Yanlei Ma
Journal:  Ann Surg Oncol       Date:  2012-07-03       Impact factor: 5.344

8.  Short- and long-term impact of body mass index on laparoscopic rectal cancer surgery.

Authors:  Q Denost; L Quintane; E Buscail; M Martenot; C Laurent; E Rullier
Journal:  Colorectal Dis       Date:  2013-04       Impact factor: 3.788

9.  Randomized clinical trial comparing laparoscopic and open surgery in patients with rectal cancer.

Authors:  J Lujan; G Valero; Q Hernandez; A Sanchez; M D Frutos; P Parrilla
Journal:  Br J Surg       Date:  2009-09       Impact factor: 6.939

Review 10.  Experts reviews of the multidisciplinary consensus conference colon and rectal cancer 2012: science, opinions and experiences from the experts of surgery.

Authors:  C J H van de Velde; P G Boelens; P J Tanis; E Espin; P Mroczkowski; P Naredi; L Pahlman; H Ortiz; H J Rutten; A J Breugom; J J Smith; A Wibe; T Wiggers; V Valentini
Journal:  Eur J Surg Oncol       Date:  2013-11-08       Impact factor: 4.424

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  3 in total

1.  The impact of robotic colorectal surgery in obese patients: a systematic review, meta-analysis, and meta-regression.

Authors:  Ian Jun Yan Wee; Li-Jen Kuo; James Chi-Yong Ngu
Journal:  Surg Endosc       Date:  2019-07-25       Impact factor: 4.584

2.  Assessing the role of robotic proctectomy in obese patients: a contemporary NSQIP analysis.

Authors:  Alexa C Glencer; Joseph A Lin; Karen Trang; Anya Greenberg; Kimberly S Kirkwood; Mohamed Abdelgadir Adam; Ankit Sarin
Journal:  J Robot Surg       Date:  2022-02-11

Review 3.  Obese patients and robotic colorectal surgery: systematic review and meta-analysis.

Authors:  Y Suwa; M Joshi; L Poynter; I Endo; H Ashrafian; A Darzi
Journal:  BJS Open       Date:  2020-09-21
  3 in total

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