Lauren M Hickling1, Rocio Perez-Iglesias1, Ann McNeill2, Lynne Dawkins3, John Moxham4, Tamatha Ruffell1, Kyra-Verena Sendt1, Philip McGuire1. 1. Department of Psychosis Studies,Institute of Psychiatry,Psychology & Neuroscience,King's College London,London,UK. 2. Addictions Department,Institute of Psychiatry,Psychology & Neuroscience,King's College London,London,UK. 3. Psychology Division,School of Applied Sciences,London South Bank University,London,UK. 4. Division of Asthma,Allergy & Lung Biology,King's College London,London,UK.
Abstract
BACKGROUND: Smoking is the largest single contributor to poor physical health and increased mortality in people with serious mental illnesses. The aim of the study was to investigate the utility of electronic cigarettes (e-cigarettes) as a harm reduction intervention in this population. METHOD: Fifty tobacco smokers with a psychotic disorder were enrolled onto a 24-week pilot study (ClinicalTrials.gov: NCT02212041) investigating the efficacy of a 6-week free e-cigarette intervention to reduce smoking. Cigarette and e-cigarette use was self-reported at weekly visits, and verified using carbon monoxide tests. Psychopathology, e-cigarette acceptability and adverse effects were assessed using standardised scales. RESULTS: There was a significant (⩾50%) reduction in cigarettes consumed per day between baseline and week 6 [F(2.596,116.800) = 25.878, p < 0.001], and e-cigarette use was stable during this period [F(2.932,46.504) = 2.023, p = 0.115]. These changes were verified by significant carbon monoxide reductions between these time points [F(3.335,126.633) = 5.063, p = 0.002]. CONCLUSIONS: The provision of e-cigarettes is a potentially useful harm reduction intervention in smokers with a psychotic disorder.
BACKGROUND: Smoking is the largest single contributor to poor physical health and increased mortality in people with serious mental illnesses. The aim of the study was to investigate the utility of electronic cigarettes (e-cigarettes) as a harm reduction intervention in this population. METHOD: Fifty tobacco smokers with a psychotic disorder were enrolled onto a 24-week pilot study (ClinicalTrials.gov: NCT02212041) investigating the efficacy of a 6-week free e-cigarette intervention to reduce smoking. Cigarette and e-cigarette use was self-reported at weekly visits, and verified using carbon monoxide tests. Psychopathology, e-cigarette acceptability and adverse effects were assessed using standardised scales. RESULTS: There was a significant (⩾50%) reduction in cigarettes consumed per day between baseline and week 6 [F(2.596,116.800) = 25.878, p &lt; 0.001], and e-cigarette use was stable during this period [F(2.932,46.504) = 2.023, p = 0.115]. These changes were verified by significant carbon monoxide reductions between these time points [F(3.335,126.633) = 5.063, p = 0.002]. CONCLUSIONS: The provision of e-cigarettes is a potentially useful harm reduction intervention in smokers with a psychotic disorder.
Authors: Sarah I Pratt; Joelle C Ferron; Mary F Brunette; Meghan Santos; James Sargent; Haiyi Xie Journal: Nicotine Tob Res Date: 2022-08-06 Impact factor: 5.825
Authors: Christine F McDonald; Stuart Jones; Lutz Beckert; Billie Bonevski; Tanya Buchanan; Jack Bozier; Kristin V Carson-Chahhoud; David G Chapman; Claudia C Dobler; Juliet M Foster; Paul Hamor; Sandra Hodge; Peter W Holmes; Alexander N Larcombe; Henry M Marshall; Gabrielle B McCallum; Alistair Miller; Philip Pattemore; Robert Roseby; Hayley V See; Emily Stone; Bruce R Thompson; Miranda P Ween; Matthew J Peters Journal: Respirology Date: 2020-07-26 Impact factor: 6.424