Literature DB >> 2998584

The cytogenetics of Wilms' tumor.

R M Slater.   

Abstract

A close association has been demonstrated between the congenital deletion 11p13 and predisposition to Wilms' tumor. Recent cytogenetic studies on Wilms' tumor cells from normal children strongly suggests that somatic changes in the short arm of chromosome #11 play an important role in the development of this tumor. The application of improved cytogenetic techniques coupled with molecular biologic analysis may help resolve questions regarding the requirement of additional changes (to alterations of 11p13) in order to evoke complete transformation leading to malignancy.

Entities:  

Mesh：

Year:  1986        PMID： 2998584     DOI： 10.1016/0165-4608(86)90369-9

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  5 in total

1.  Constitutional extra chromosomal element in a family with Wilms' tumor.

Authors:  S Kakati; H Xiao; S Y Siddiqui; C Sreekantaiah; H U Weier; D M Green; J E Fisher; J E Allen
Journal:  Hum Genet       Date:  1991-06       Impact factor: 4.132

2.  Cell culture studies on neurofibromatosis (von Recklinghausen). V. Monosomy 22 and other chromosomal anomalies in cultures from peripheral neurofibromas.

Authors:  W Krone; I Högemann
Journal:  Hum Genet       Date:  1986-12       Impact factor: 4.132

3.  Genetic mechanisms of tumor-specific loss of 11p DNA sequences in Wilms tumor.

Authors:  D D Dao; W T Schroeder; L Y Chao; H Kikuchi; L C Strong; V M Riccardi; S Pathak; W W Nichols; W H Lewis; G F Saunders
Journal:  Am J Hum Genet       Date:  1987-08       Impact factor: 11.025

4.  Cytogenetic investigations of solid tumours of children.

Authors:  A D Pearson; M M Reid; E V Davison; N Bown; A J Malcolm; A W Craft
Journal:  Arch Dis Child       Date:  1988-09       Impact factor: 3.791

Review 5.  Recessive mechanisms of malignancy.

Authors:  A R Green
Journal:  Br J Cancer       Date:  1988-08       Impact factor: 7.640
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.