Literature DB >> 29984645

Porous Inorganic and Hybrid Systems for Drug Delivery: Future Promise in Combatting Drug Resistance and Translation to Botanical Applications.

Junling Guo1,2, Bruno D Mattos3, Blaise L Tardy3, Vanessa M Moody4, Gao Xiao2,5, Hirotaka Ejima6, Jiwei Cui1, Kang Liang7,8,9, Joseph J Richardson6,10.   

Abstract

BACKGROUND: Porous micro- and nanoparticles have the capacity to encapsulate a large quantity of therapeutics, making them promising delivery vehicles for a variety of applications. This review aims to highlight the latest development of inorganic and hybrid (inorganic/ organic) particles for drug delivery with an additional emphasis on combatting drug resistant cancer. We go one step further and discuss delivery applications beyond medicinal delivery, as there is generally a translation from medicinal delivery to botanic delivery after a short lag time.
METHODS: We undertook a search of relevant peer-reviewed publications. The quality of the relevant papers was appraised using standard tools. The characteristics of the papers are described herein, and the relevant material and therapeutic properties are discussed.
RESULTS: We discuss 4 classes of porous particles in terms of drug delivery and theranostics. We specifically focus on silica, calcium carbonate, metal-phenolic network, and metalorganic framework particles. Other relevant biomedically relevant applications are discussed and we highlight outstanding therapeutic results in the relevant literature.
CONCLUSION: The findings of this review confirm the importance of studying and utilizing porous particles for therapeutic delivery. Moreover, we show that the properties of porous particles that make them promising for medicinal drug delivery also make them promising candidates for agro-industrial applications. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Nanomedicine; botanic delivery; drug delivery; hybrid; inorganic; porous particles.

Year:  2019        PMID: 29984645     DOI: 10.2174/0929867325666180706111909

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  5 in total

1.  Metal-Phenolic Network-Functionalized Magnetic Nanoparticles for Enzyme Immobilization.

Authors:  Jian Li; Lin Han; Tiantian Feng; Min Zhang; Tao Jiang
Journal:  Appl Biochem Biotechnol       Date:  2022-06-25       Impact factor: 3.094

Review 2.  Recent Trends in Covalent and Metal Organic Frameworks for Biomedical Applications.

Authors:  Georges Chedid; Ali Yassin
Journal:  Nanomaterials (Basel)       Date:  2018-11-07       Impact factor: 5.076

3.  Self-assembly of nanomicelles with rationally designed multifunctional building blocks for synergistic chemo-photodynamic therapy.

Authors:  Guidong Gong; Jiezhou Pan; Yunxiang He; Jiaojiao Shang; Xiaoling Wang; Yaoyao Zhang; Guolin Zhang; Fei Wang; Gang Zhao; Junling Guo
Journal:  Theranostics       Date:  2022-01-31       Impact factor: 11.556

4.  Oxygen and Drug-Carrying Periodic Mesoporous Organosilicas for Enhanced Cell Viability under Normoxic and Hypoxic Conditions.

Authors:  Ravi Kumar; Nermin Seda Kehr
Journal:  Int J Mol Sci       Date:  2022-04-14       Impact factor: 6.208

5.  Eu-Doped Citrate-Coated Carbonated Apatite Luminescent Nanoprobes for Drug Delivery.

Authors:  Ylenia Jabalera; Francesca Oltolina; Maria Prat; Concepcion Jimenez-Lopez; Jorge F Fernández-Sánchez; Duane Choquesillo-Lazarte; Jaime Gómez-Morales
Journal:  Nanomaterials (Basel)       Date:  2020-01-23       Impact factor: 5.076

  5 in total

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