Literature DB >> 29984626

The role of the pharmacist in the multidisciplinary approach to the prevention and resolution of drug-related problems in cancer chemotherapy.

Ahmet S Boşnak1, Nevzat Birand1, Ömer Diker2, Abdikarim Abdi1, Bilgen Başgut1.   

Abstract

BACKGROUND: Clinical pharmacists have important roles in implementing scientifically valid knowledge and advice on safe, reasonable use of pharmaceuticals. Clinical pharmacy services were introduced and evaluated in oncology clinic in a tertiary university hospital.
METHODS: A prospective interventional study was conducted from November 2017 to March 2018. Drug-related problems were classified using the Pharmaceutical Care Network Europe drug-related problem classification tool v8.01. The main outcome measure is the proposed interventions aimed at identification of the drug-related problems, the role of the pharmacists in the resolution, and the rate of acceptance of these recommendations by physicians.
RESULTS: A total of 102 patients were included in the study, who were treated with at least two cycles of any cancer type and stage. A total of 55 (53.9%) patients had 251 drug-related problems. Drug-related problems mainly involved antihypertensive (31.6%), antidiabetic (17.8%), and herbal agents (31.6%). Treatment effectiveness was the major type of drug-related problems (50.2%) followed by treatment safety (29.1%). A total of 211 (100%) interventions were accepted and regarded as clinically relevant. Prescriber informed only were the most common types of intervention at the prescriber level. Eighty-six point four percent identified drug-related problems were solved, 9.8% of the problems were partially solved, 2.3% problems were unsolved.
CONCLUSION: Clinical pharmacy services may have optimized therapy effectiveness, prevent adverse effects and unclear/compliant problems. The pharmacist interventions were highly acknowledged by oncologists and patients; this may indicate the presence of a great convenience and need to implement Clinical pharmacy services in alternative hospitals in Northern Cyprus.

Entities:  

Keywords:  Oncology pharmacy; chemotherapy; clinical pharmacy services; drug-related problems

Mesh:

Substances:

Year:  2018        PMID: 29984626     DOI: 10.1177/1078155218786048

Source DB:  PubMed          Journal:  J Oncol Pharm Pract        ISSN: 1078-1552            Impact factor:   1.809


  6 in total

1.  Evaluation of Medication Instruction Sheets for Patients Undergoing R-CHOP Therapy in Non-Hodgkin's Lymphoma.

Authors:  Mayako Uchida; Rika Kawai; Rie Hisamitsu; Sayaka Mai; Shigeru Ishida; Hiroyuki Watanabe; Takehiro Kawashiri; Koji Kato; Keiko Hosohata; Toshihiro Miyamoto; Nobuaki Egashira; Tsutomu Nakamura; Koichi Akashi; Ichiro Ieiri
Journal:  In Vivo       Date:  2022 May-Jun       Impact factor: 2.406

2.  Impact of clinical pharmacist services on quality adjusted life years in head and neck cancer patients.

Authors:  Avinash Khadela; Bhavin Vyas; Vishal Bhikadiya; Prakshavi Naik
Journal:  Int J Clin Pharm       Date:  2021-02-02

3.  Evaluation of pharmacist interventions and commonly used medications in the geriatric ward of a teaching hospital in Turkey: a retrospective study.

Authors:  Elif Ertuna; Mehmet Zuhuri Arun; Seval Ay; Fatma Özge Kayhan Koçak; Bahattin Gökdemir; Gül İspirli
Journal:  Clin Interv Aging       Date:  2019-03-21       Impact factor: 4.458

4.  Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia.

Authors:  Malede Berihun Yismaw; Haileyesus Adam; Ephrem Engidawork
Journal:  J Oncol       Date:  2020-03-16       Impact factor: 4.375

5.  Integrating the clinical pharmacist into the emergency department interdisciplinary team: a study protocol for a multicentre trial applying a non-randomised stepped-wedge study design.

Authors:  Renata Vesela; Renate Elenjord; Elin C Lehnbom; Eirik Hugaas Ofstad; Tine Johnsgård; Birgitte Zahl-Holmstad; Torstein Risør; Torbjørn Wisløff; Lars Røslie; Ole Magnus Filseth; Per-Christian Valle; Kristian Svendsen; Hanne Mathilde Frøyshov; Beate H Garcia
Journal:  BMJ Open       Date:  2021-11-25       Impact factor: 2.692

6.  Pharmacists' Knowledge and Practice of Issues Related to Using Psychotropic Medication in Elderly People in Ethiopia: A Prospective Cross-Sectional Study.

Authors:  Gashaw Binega Mekonnen; Alemante Tafese Beyna
Journal:  Biomed Res Int       Date:  2020-08-12       Impact factor: 3.411

  6 in total

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