The hands are the most commonly affected area in burn injuries and are involved approximately 80% of the time. Because of the thinness of the skin and superficial location of critical structures, the dorsum of the hand needs an optimal coverage to preserve maximum articular mobility and range of motion. The aim of this article is to detail the therapeutic alternatives to skin graft in cases of very deep burns on the dorsum of the hand, and to specify the indications. We reviewed all articles referenced on PubMed, and included all the original articles related to the management of acute burned hands and their different coverage techniques (dermal substitutes and flaps). We excluded articles that dealt only with skin grafting techniques, as well as articles about secondary management (sequelae and reconstruction). One hundred and sixteen articles were found and twenty of these were selected. Alternatives to full-thickness skin grafting are dermal substitutes (Alloderm®, Matriderm®, Integra®) and flaps. In cases of immediately usable autologous donor sites, the combination Matriderm® with a thin skin graft is preferred. Otherwise, we use Integra®. In cases of deep exposure of critical structures and doubtful vascularization quality on the wound, flaps can be discussed (cross-arm, abdominal wall flap…).