Literature DB >> 29982115

The eLoaD platform endows centrifugal microfluidics with on-disc power and communication.

Saraí M Torres Delgado1, Jan G Korvink2, Dario Mager3.   

Abstract

In this paper we present a comprehensive description of the design, fabrication and operation of an electrified Lab-on-a-Disc (eLoaD) system. The smart platform is developed to extend conventional Lab-on-a-Disc applications with an electronic interface, providing additional flow control and sensing capabilities to centrifugal microfluidics platforms. Wireless power is transferred from a Qi-compliant transmitter to the eLoaD platform during rotation. An Arduino-based microcontroller, a Bluetooth communication module, and an on-board SD-card are integrated into the platform. This generalises the applicability of the eLoaD and its modules for performing a wide range of laboratory unit operations, procedures, or diagnostic assays, all controlled wirelessly during spinning. The lightweight platform is fully reusable and modular in design and construction. An interchangeable and non-disposable application disc is fitted with the necessary sensors and/or actuators for a specific assay or experiment to be performed. A particular advantage is the ability to continuously monitor and interact with LoaD experiments, overcoming the limitations of stroboscopy. We demonstrate the applicability of the platform for three sensing experiments involving optical, electrochemical, and temperature detection, and one actuation experiment involving controlled heating/cooling. The complete electronic designs and example programming codes are extensively documented in the supplementary material for easy adaptation.
Copyright © 2018 Elsevier B.V. All rights reserved.

Keywords:  Automation; Centrifugal platform; Lab-on-a-Disc; On-disc; Wireless

Mesh:

Year:  2018        PMID: 29982115     DOI: 10.1016/j.bios.2018.05.056

Source DB:  PubMed          Journal:  Biosens Bioelectron        ISSN: 0956-5663            Impact factor:   10.618


  2 in total

1.  Design and fabrication of a low-cost wireless camera imaging system for centrifugal microfluidics.

Authors:  Brian Regan; David Kinahan; Philip Daly; Richard O'Kennedy; David Collins
Journal:  HardwareX       Date:  2022-01-08

2.  Evaluating carbon-electrode dielectrophoresis under the ASSURED criteria.

Authors:  Rodrigo Martinez-Duarte; Dario Mager; Jan G Korvink; Monsur Islam
Journal:  Front Med Technol       Date:  2022-07-26
  2 in total

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