Literature DB >> 29981245

Current and future treatment of hidradenitis suppurativa.

K R van Straalen1, S Schneider-Burrus2,3, E P Prens1.   

Abstract

This scholarly review on the current and future treatment of hidradenitis suppurativa (HS) focuses on medical and surgical treatment options, while novel pipeline drugs are also discussed. Treatment goals are to limit the incidence and duration of flares, reducing inflammation and suppuration, achieving local cure after surgery and, most importantly, to improve the quality of life of patients with HS. The type of medication and/or surgery should be chosen based on the stage of the disease and the degree of inflammation. However, the lack of a simple scoring system and the lack of clear surgical outcome definitions hamper the interpretation of treatment efficacy and the comparison between different treatment strategies. The therapeutic pipeline for HS is gradually expanding, and will probably lead to a broader panel of more effective therapeutic options.
© 2018 British Association of Dermatologists.

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Year:  2018        PMID: 29981245     DOI: 10.1111/bjd.16768

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  7 in total

1.  The surgeon’s perspective: a retrospective study of wide local excisions taken to healthy subcutaneous fat in the management of advanced hidradenitis suppurativa

Authors:  Eran Shavit; Andrew Pawliwec; Afsaneh Alavi; Ralph George
Journal:  Can J Surg       Date:  2020-02-28       Impact factor: 2.089

2.  Contribution of fibroblasts to tunnel formation and inflammation in hidradenitis suppurativa/ acne inversa.

Authors:  John W Frew; Kristina Navrazhina; Meaghan Marohn; Pei-Ju C Lu; James G Krueger
Journal:  Exp Dermatol       Date:  2019-07-03       Impact factor: 3.960

Review 3.  Medical Management of Hidradenitis Suppurativa with Non-Biologic Therapy: What's New?

Authors:  Soha Ghanian; Mika Yamanaka-Takaichi; Haley B Naik; Afsaneh Alavi
Journal:  Am J Clin Dermatol       Date:  2022-01-06       Impact factor: 6.233

4.  Hidradenitis Suppurativa: A Systematic Review Integrating Inflammatory Pathways Into a Cohesive Pathogenic Model.

Authors:  Allard R J V Vossen; Hessel H van der Zee; Errol P Prens
Journal:  Front Immunol       Date:  2018-12-14       Impact factor: 7.561

Review 5.  Therapies for hidradenitis suppurativa: a systematic review with a focus on Brazil.

Authors:  Maria Cecilia Rivitti-Machado; Renata Ferreira Magalhães; Roberto Souto da Silva; Gleison V Duarte; Fabiana Zs Bosnich; Roberto Gaspar Tunala; Francisco José Forestiero
Journal:  Drugs Context       Date:  2022-01-19

6.  Communicating with health providers and romantic partners: The impact of negative emotions on quality of life for individuals with hidradenitis suppurativa.

Authors:  Natalie Ingraham; Lena R Hann; J Austin Williamson; Caleb Drew
Journal:  Int J Womens Dermatol       Date:  2022-10-07

7.  Identifying Unmet Care Needs and Important Treatment Attributes in the Management of Hidradenitis Suppurativa: A Qualitative Interview Study.

Authors:  Damon Willems; Mickael Hiligsmann; Hessel H van der Zee; Christopher J Sayed; Silvia M A A Evers
Journal:  Patient       Date:  2021-08-09       Impact factor: 3.883

  7 in total

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