Literature DB >> 29980891

Lymphedema surgery: the current state of the art.

Jay W Granzow1.   

Abstract

BACKGROUND/
PURPOSE: Lymphedema surgery, when integrated into a comprehensive lymphedema treatment program for patients, can provide effective and long-term improvements that non-surgical management alone cannot achieve. Such a treatment program can provide significant improvement for many issues such as recurring cellulitis infections, inability to wear clothing appropriate for the rest of their body size, loss of function of arm or leg, and desire to decrease the amount of lymphedema therapy and compression garment use.
METHODS: The fluid predominant portion of lymphedema may be treated effectively with surgeries that involve transplantation of lymphatic tissue, called vascularized lymph node transfer (VLNT), or involve direct connections from the lymphatic system to the veins, called lymphaticovenous anastomoses (LVA). VLNT and LVA are microsurgical procedures that can improve the patient's own physiologic drainage of the lymphatic fluid, and we have seen the complete elimination for the need of compression garments in some of our patients. These procedures tend to have better results when performed when a patient's lymphatic system has less damage. The stiff, solid-predominant swelling often found in later stages of lymphedema can be treated effectively with a surgery called suction-assisted protein lipectomy (SAPL). SAPL surgeries allow removal of lymphatic solids and fatty deposits that are otherwise poorly treated by conservative lymphedema therapy, VLNT or LVA surgeries.
CONCLUSION: Overall, multiple effective surgical options for lymphedema exist. Surgical treatments should not be seen as a "quick fix", and should be pursued in the framework of continuing lymphedema therapy and treatment to optimize each patient's outcome. When performed by an experienced lymphedema surgeon as part of an integrated system with expert lymphedema therapy, safe, consistent and long-term improvements can be achieved.

Entities:  

Keywords:  LVA; Lymph node transfer; Lymphedema surgery; SAPL; VLNT

Mesh:

Year:  2018        PMID: 29980891     DOI: 10.1007/s10585-018-9897-7

Source DB:  PubMed          Journal:  Clin Exp Metastasis        ISSN: 0262-0898            Impact factor:   5.150


  40 in total

Review 1.  Overview of surgical treatments for breast cancer-related lymphedema.

Authors:  Hiroo Suami; David W Chang
Journal:  Plast Reconstr Surg       Date:  2010-12       Impact factor: 4.730

Review 2.  From lymph to fat: liposuction as a treatment for complete reduction of lymphedema.

Authors:  Håkan Brorson
Journal:  Int J Low Extrem Wounds       Date:  2012-02-23       Impact factor: 2.057

3.  An effective system of surgical treatment of lymphedema.

Authors:  Jay W Granzow; Julie M Soderberg; Amy H Kaji; Christine Dauphine
Journal:  Ann Surg Oncol       Date:  2014-02-13       Impact factor: 5.344

4.  Skin blood flow of the lymphedematous arm before and after liposuction.

Authors:  H Brorson; H Svensson
Journal:  Lymphology       Date:  1997-12       Impact factor: 1.286

5.  A novel approach to the treatment of lower extremity lymphedema by transferring a vascularized submental lymph node flap to the ankle.

Authors:  Ming-Huei Cheng; Jung-Ju Huang; Ju-Jung Huang; Dung H Nguyen; Michel Saint-Cyr; Michael R Zenn; Bien Keem Tan; Chyi-Long Lee
Journal:  Gynecol Oncol       Date:  2012-04-17       Impact factor: 5.482

Review 6.  Review of current surgical treatments for lymphedema.

Authors:  Jay W Granzow; Julie M Soderberg; Amy H Kaji; Christine Dauphine
Journal:  Ann Surg Oncol       Date:  2014-02-21       Impact factor: 5.344

7.  Postmastectomy lymphedema: long-term results following microsurgical lymph node transplantation.

Authors:  Corinne Becker; Jalal Assouad; Marc Riquet; Geneviève Hidden
Journal:  Ann Surg       Date:  2006-03       Impact factor: 12.969

8.  A microsurgical method for reconstruction of interrupted lymphatic pathways: autologous lymph-vessel transplantation for treatment of lymphedemas.

Authors:  R G Baumeister; S Siuda; H Bohmert; E Moser
Journal:  Scand J Plast Reconstr Surg       Date:  1986

9.  Liposuction for Advanced Lymphedema: A Multidisciplinary Approach for Complete Reduction of Arm and Leg Swelling.

Authors:  John Boyages; Katrina Kastanias; Louise A Koelmeyer; Caleb J Winch; Thomas C Lam; Kerry A Sherman; David Alex Munnoch; Håkan Brorson; Quan D Ngo; Asha Heydon-White; John S Magnussen; Helen Mackie
Journal:  Ann Surg Oncol       Date:  2015-06-30       Impact factor: 5.344

10.  Higher vascular endothelial growth factor-C concentration in plasma is associated with increased forearm capillary filtration capacity in breast cancer-related lymphedema.

Authors:  Mads Radmer Jensen; Lene Simonsen; Tonny Karlsmark; Charlotte Lanng; Jens Bülow
Journal:  Physiol Rep       Date:  2015-06
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  9 in total

1.  Lipedema and Dercum's Disease: A New Application of Bioimpedance.

Authors:  Rachelle Crescenzi; Paula M C Donahue; Sandra Weakley; Maria Garza; Manus J Donahue; Karen L Herbst
Journal:  Lymphat Res Biol       Date:  2019-08-13       Impact factor: 2.589

Review 2.  Lymphaticovenular anastomosis for breast cancer-related upper extremity lymphedema: a literature review.

Authors:  Antonio J Forte; Andrea Sisti; Maria T Huayllani; Daniel Boczar; Gabriela Cinotto; Pedro Ciudad; Oscar J Manrique; Xiaona Lu; Sarah McLaughlin
Journal:  Gland Surg       Date:  2020-04

Review 3.  Breast Cancer-Related Lymphedema: Risk Factors, Screening, Management, and the Impact of Locoregional Treatment.

Authors:  Sarah A McLaughlin; Cheryl L Brunelle; Alphonse Taghian
Journal:  J Clin Oncol       Date:  2020-05-22       Impact factor: 44.544

4.  Treatment of Early-Stage Gynecological Cancer-Related Lower Limb Lymphedema by Lymphaticovenular Anastomosis-The Triple Incision Approach.

Authors:  Anna Amelia Caretto; Gianluigi Stefanizzi; Giorgia Garganese; Simona Maria Fragomeni; Alex Federico; Luca Tagliaferri; Bruno Fionda; Alessandro Cina; Giovanni Scambia; Stefano Gentileschi
Journal:  Medicina (Kaunas)       Date:  2022-05-01       Impact factor: 2.948

Review 5.  Secondary lymphedema from cancer therapy.

Authors:  Michael Bernas; Saskia R J Thiadens; Paula Stewart; Jay Granzow
Journal:  Clin Exp Metastasis       Date:  2021-05-05       Impact factor: 5.150

Review 6.  Development and Themes of Diagnostic and Treatment Procedures for Secondary Leg Lymphedema in Patients with Gynecologic Cancers.

Authors:  Yumiko Watanabe; Masafumi Koshiyama; Keiko Seki; Miwa Nakagawa; Eri Ikuta; Makiko Oowaki; Shin-Ichi Sakamoto
Journal:  Healthcare (Basel)       Date:  2019-08-27

7.  Comparison of avascular lymph node fragment transplantation techniques to optimize lymphangiogenesis in the minipig model.

Authors:  Catarina Hadamitzky; Frank Bruns; Klaus-Friedrich Gratz; Lia Schindewolffs; Katrin S Roth; Martin Werner; Kristiana Gordon; Peter M Vogt; Reinhard Pabst
Journal:  Eur J Plast Surg       Date:  2021-10-12

8.  Assessment of Lymphovenous Anastomosis Patency: Technical Highlights.

Authors:  Antonio J Forte; Maria T Huayllani; Andrea Sisti; Daniel Boczar; Pedro Ciudad; Oscar J Manrique; Rudolf F Buntic
Journal:  Plast Reconstr Surg Glob Open       Date:  2020-03-27

9.  Lymphedema Liposuction with Immediate Limb Contouring.

Authors:  Wei F Chen; Wei-Feng Zeng; Patrick J Hawkes; Jeanette Man; Mindy Bowen
Journal:  Plast Reconstr Surg Glob Open       Date:  2019-11-12
  9 in total

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