Xiao Du1, Xiang-Hui Fu2, Bo-Qiang Peng3, Rong Luo3, Jian-Kun Hu1, Zhong Cheng4. 1. Department of Gastrointestinal Surgery, Laboratory of Bariatric and Metabolic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China. 2. Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, P.R. China. 3. Gastrointestinal Tract Reconstruction and Metabolic Surgery Association, West China Medical School, West China Hospital, Sichuan University, Chengdu, P.R. China. 4. Department of Gastrointestinal Surgery, Laboratory of Bariatric and Metabolic Surgery, West China Hospital, Sichuan University, Chengdu, P.R. China. Electronic address: zhongcheng1963@126.com.
Abstract
BACKGROUND: The effects of laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) on metabolic syndrome (MS) in morbidly obese patients have not been well studied. OBJECTIVE: To compare the effectiveness of LSG and LRYGB in Chinese morbidly obese patients with MS. SETTING: University Hospital, China. METHODS: Patients who underwent LRYGB or LSG surgery and had completed at least 1 year of follow-up were retrospectively reviewed. Bariatric and metabolic outcomes in the 2 groups were compared. Univariate and multivariate analyses were performed to identify the predictors of MS remission. RESULTS: Of the 176 patients enrolled in this study, 79 underwent LSG and 97 underwent LRYGB. Eighty-three met 3 of the International Diabetes Federation criteria for diagnosis of MS, 69 met 4 of the criteria, and 24 met 5 of the criteria. At 1 year after bariatric surgery, 79% of patients achieved remission of MS. In both LSG and LRYGB groups, the number of MS criteria met by patients decreased significantly after surgery. The MS remission rate was not significantly different between the 2 groups (74.7% in LSG versus 82.5% in LGB; P = .21). In LSG patients, there was no significant decrease in blood pressure or increase in the high-density lipoprotein cholesterol at 1 year. On logistic regression analysis, younger age, lower body mass index, and lower homeostatic model of assessment-insulin resistance were independently associated with MS remission at 1 year after surgery. Both groups showed satisfactory and comparable weight loss (percentage of excess weight loss: 71.7% in LSG versus 74.4% in LRYGB). No surgery-related mortality occurred. CONCLUSIONS: Both LSG and LRYGB are feasible, safe, and effective in Chinese obese patients with MS. LSG seems to be inferior to LRYGB with regard to control of hypertension and high-density lipoprotein cholesterol.
BACKGROUND: The effects of laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB) on metabolic syndrome (MS) in morbidly obesepatients have not been well studied. OBJECTIVE: To compare the effectiveness of LSG and LRYGB in Chinese morbidly obesepatients with MS. SETTING: University Hospital, China. METHODS:Patients who underwent LRYGB or LSG surgery and had completed at least 1 year of follow-up were retrospectively reviewed. Bariatric and metabolic outcomes in the 2 groups were compared. Univariate and multivariate analyses were performed to identify the predictors of MS remission. RESULTS: Of the 176 patients enrolled in this study, 79 underwent LSG and 97 underwent LRYGB. Eighty-three met 3 of the International Diabetes Federation criteria for diagnosis of MS, 69 met 4 of the criteria, and 24 met 5 of the criteria. At 1 year after bariatric surgery, 79% of patients achieved remission of MS. In both LSG and LRYGB groups, the number of MS criteria met by patients decreased significantly after surgery. The MS remission rate was not significantly different between the 2 groups (74.7% in LSG versus 82.5% in LGB; P = .21). In LSG patients, there was no significant decrease in blood pressure or increase in the high-density lipoprotein cholesterol at 1 year. On logistic regression analysis, younger age, lower body mass index, and lower homeostatic model of assessment-insulin resistance were independently associated with MS remission at 1 year after surgery. Both groups showed satisfactory and comparable weight loss (percentage of excess weight loss: 71.7% in LSG versus 74.4% in LRYGB). No surgery-related mortality occurred. CONCLUSIONS: Both LSG and LRYGB are feasible, safe, and effective in Chinese obesepatients with MS. LSG seems to be inferior to LRYGB with regard to control of hypertension and high-density lipoprotein cholesterol.
Authors: Nataly Echevarria-Castro; Kevin Silva-Parra; Marcos Polar-Trinidad; Juan C Sánchez-Vicente; Gustavo Salinas-Sedo; Carlos J Toro-Huamanchumo Journal: J Clin Med Date: 2022-08-11 Impact factor: 4.964
Authors: Abdulrahman O Alomar; Mohammed F Shaheen; Abdallh S Almaneea; Eyad K Althaqeb; Ziyad M Alshahrani; Yazeed A Jarman; Sultan Alhabdan Journal: Obes Surg Date: 2021-05-27 Impact factor: 4.129