Literature DB >> 29980141

Wnt signaling pathway in development and cancer.

B Taciak1, I Pruszynska1, L Kiraga1, M Bialasek1, M Krol2.   

Abstract

Wnt signaling pathway is one of the most important signaling pathways. The complexity of Wnt signals and their functional role is crucial in development and growth. It is the most active during embryogenesis facilitating new organism formation by cell differentiation, polarization and migration. Its activation is also common during development of many tumors and others diseases. In this review we shortly describe a role of Wnt pathway in development in order to better understand its role in cancer progression. We also describe current anti-cancer therapies targeting Wnt pathway.

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Year:  2018        PMID： 29980141     DOI： 10.26402/jpp.2018.2.07

Source DB:  PubMed          Journal:  J Physiol Pharmacol        ISSN： 0867-5910            Impact factor:   3.011


  58 in total

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