Literature DB >> 29979991

Th17 Cells in Parkinson's Disease: The Bane of the Midbrain.

Ashley C Bolte1, John R Lukens2.   

Abstract

Emerging data implicate potential roles for T cells in Parkinson's disease (PD); however, direct evidence for human T cells in PD-associated neurodegeneration has been lacking. In this issue of Cell Stem Cell, Sommer et al. (2018) demonstrate that IL-17-producing T cells from sporadic PD patients promote cell death of patient iPSC-derived midbrain neurons.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 29979991      PMCID： PMC7839142          DOI： 10.1016/j.stem.2018.06.016

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  10 in total

1.  Th17 Cells Induce Dopaminergic Neuronal Death via LFA-1/ICAM-1 Interaction in a Mouse Model of Parkinson's Disease.

Authors:  Zhan Liu; Yan Huang; Bei-Bei Cao; Yi-Hua Qiu; Yu-Ping Peng
Journal:  Mol Neurobiol       Date:  2016-11-14       Impact factor: 5.590

2.  Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease.

Authors:  Annika Sommer; Franz Marxreiter; Florian Krach; Tanja Fadler; Janina Grosch; Michele Maroni; Daniela Graef; Esther Eberhardt; Markus J Riemenschneider; Gene W Yeo; Zacharias Kohl; Wei Xiang; Fred H Gage; Jürgen Winkler; Iryna Prots; Beate Winner
Journal:  Cell Stem Cell       Date:  2018-07-05       Impact factor: 24.633

3.  Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.

Authors:  Timothy R Sampson; Justine W Debelius; Taren Thron; Stefan Janssen; Gauri G Shastri; Zehra Esra Ilhan; Collin Challis; Catherine E Schretter; Sandra Rocha; Viviana Gradinaru; Marie-Francoise Chesselet; Ali Keshavarzian; Kathleen M Shannon; Rosa Krajmalnik-Brown; Pernilla Wittung-Stafshede; Rob Knight; Sarkis K Mazmanian
Journal:  Cell       Date:  2016-12-01       Impact factor: 41.582

4.  Induction of intestinal Th17 cells by segmented filamentous bacteria.

Authors:  Ivaylo I Ivanov; Koji Atarashi; Nicolas Manel; Eoin L Brodie; Tatsuichiro Shima; Ulas Karaoz; Dongguang Wei; Katherine C Goldfarb; Clark A Santee; Susan V Lynch; Takeshi Tanoue; Akemi Imaoka; Kikuji Itoh; Kiyoshi Takeda; Yoshinori Umesaki; Kenya Honda; Dan R Littman
Journal:  Cell       Date:  2009-10-30       Impact factor: 41.582

5.  Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease.

Authors:  Vanessa Brochard; Béhazine Combadière; Annick Prigent; Yasmina Laouar; Aline Perrin; Virginie Beray-Berthat; Olivia Bonduelle; Daniel Alvarez-Fischer; Jacques Callebert; Jean-Marie Launay; Charles Duyckaerts; Richard A Flavell; Etienne C Hirsch; Stéphane Hunot
Journal:  J Clin Invest       Date:  2008-12-22       Impact factor: 14.808

6.  MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration.

Authors:  Ashley S Harms; Shuwen Cao; Amber L Rowse; Aaron D Thome; Xinru Li; Leandra R Mangieri; Randy Q Cron; John J Shacka; Chander Raman; David G Standaert
Journal:  J Neurosci       Date:  2013-06-05       Impact factor: 6.167

Review 7.  The role of innate and adaptive immunity in Parkinson's disease.

Authors:  George T Kannarkat; Jeremy M Boss; Malú G Tansey
Journal:  J Parkinsons Dis       Date:  2013       Impact factor: 5.568

8.  Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.

Authors:  Taye H Hamza; Cyrus P Zabetian; Albert Tenesa; Alain Laederach; Jennifer Montimurro; Dora Yearout; Denise M Kay; Kimberly F Doheny; Justin Paschall; Elizabeth Pugh; Victoria I Kusel; Randall Collura; John Roberts; Alida Griffith; Ali Samii; William K Scott; John Nutt; Stewart A Factor; Haydeh Payami
Journal:  Nat Genet       Date:  2010-08-15       Impact factor: 38.330

9.  MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.

Authors:  Carolina Cebrián; Fabio A Zucca; Pierluigi Mauri; Julius A Steinbeck; Lorenz Studer; Clemens R Scherzer; Ellen Kanter; Sadna Budhu; Jonathan Mandelbaum; Jean P Vonsattel; Luigi Zecca; John D Loike; David Sulzer
Journal:  Nat Commun       Date:  2014-04-16       Impact factor: 14.919

10.  T cells from patients with Parkinson's disease recognize α-synuclein peptides.

Authors:  David Sulzer; Roy N Alcalay; Francesca Garretti; Lucien Cote; Ellen Kanter; Julian Agin-Liebes; Christopher Liong; Curtis McMurtrey; William H Hildebrand; Xiaobo Mao; Valina L Dawson; Ted M Dawson; Carla Oseroff; John Pham; John Sidney; Myles B Dillon; Chelsea Carpenter; Daniela Weiskopf; Elizabeth Phillips; Simon Mallal; Bjoern Peters; April Frazier; Cecilia S Lindestam Arlehamn; Alessandro Sette
Journal:  Nature       Date:  2017-06-21       Impact factor: 49.962
  10 in total
  7 in total

1.  Chronic maternal interleukin-17 and autism-related cortical gene expression, neurobiology, and behavior.

Authors:  Serena Banu Gumusoglu; Benjamin Wen Qing Hing; Akanksha Sri Satya Chilukuri; Jessica Jolynn Dewitt; Sabrina Marie Scroggins; Hanna Elizabeth Stevens
Journal:  Neuropsychopharmacology       Date:  2020-02-19       Impact factor: 7.853

Review 2.  The role of meningeal populations of type II innate lymphoid cells in modulating neuroinflammation in neurodegenerative diseases.

Authors:  Sherry Sin-Hang Yeung; Yuen-Shan Ho; Raymond Chuen-Chung Chang
Journal:  Exp Mol Med       Date:  2021-09-06       Impact factor: 12.153

Review 3.  Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases.

Authors:  Qing Wang; Li-Juan Song; Zhi-Bin Ding; Zhi Chai; Jie-Zhong Yu; Bao-Guo Xiao; Cun-Gen Ma
Journal:  Neural Regen Res       Date:  2022-12       Impact factor: 6.058

4.  Neuroprotective Activities of Long-Acting Granulocyte-Macrophage Colony-Stimulating Factor (mPDM608) in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Intoxicated Mice.

Authors:  Katherine E Olson; Krista L Namminga; Aaron D Schwab; Mackenzie J Thurston; Yaman Lu; Ashley Woods; Lei Lei; Weijun Shen; Feng Wang; Sean B Joseph; Howard E Gendelman; R Lee Mosley
Journal:  Neurotherapeutics       Date:  2020-10       Impact factor: 6.088

Review 5.  The role of innate lymphoid cells (ILCs) in mental health.

Authors:  Tatiana Barichello
Journal:  Discov Ment Health       Date:  2022-02-07

6.  T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson's disease.

Authors:  Meena S Subbarayan; Charles Hudson; Lauren D Moss; Kevin R Nash; Paula C Bickford
Journal:  J Neuroinflammation       Date:  2020-08-15       Impact factor: 8.322

Review 7.  Immune-microbiome interplay and its implications in neurodegenerative disorders.

Authors:  Ankit Uniyal; Vineeta Tiwari; Mousmi Rani; Vinod Tiwari
Journal:  Metab Brain Dis       Date:  2021-08-06       Impact factor: 3.584
  7 in total

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