Literature DB >> 2997981

Structure of the Epstein-Barr virus nuclear antigen as probed with monoclonal antibodies.

J C Hearing, A Lewis, A J Levine.   

Abstract

Five hybridoma cell lines secreting antibodies directed against an Epstein-Barr virus (EBV) nuclear antigen (BamHI K antigen) have been isolated. All five antibodies detect this antigen in a variety of EBV-positive lymphoblastoid cell lines. The reaction of these antibodies with several mutant forms of this protein has allowed the antibody binding site(s) to be predicted.

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Year:  1985        PMID： 2997981     DOI： 10.1016/0042-6822(85)90436-2

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  4 in total

1.  Interaction of Epstein-Barr virus nuclear antigen 1 with the viral latent origin of replication.

Authors:  J Hearing; Y Mülhaupt; S Harper
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

2.  Identification and mapping of Epstein-Barr virus early antigens and demonstration of a viral gene activator that functions in trans.

Authors:  K M Wong; A J Levine
Journal:  J Virol       Date:  1986-10       Impact factor: 5.103

3.  Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice.

Authors:  J B Wilson; J L Bell; A J Levine
Journal:  EMBO J       Date:  1996-06-17       Impact factor: 11.598

4.  EBNA-1, the major nuclear antigen of Epstein-Barr virus, resembles 'RGG' RNA binding proteins.

Authors:  D K Snudden; J Hearing; P R Smith; F A Grässer; B E Griffin
Journal:  EMBO J       Date:  1994-10-17       Impact factor: 11.598
  4 in total

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