PURPOSE: To describe a case of a large, traumatic macular hole in a pediatric patient closed using an internal limiting membrane flap in combination with autologous plasma concentrate (APC). METHODS: Description of a surgical technique as performed in one patient. RESULTS: Successful macular hole closure and improvement in postoperative visual acuity were achieved in the patient in whom the technique was performed. CONCLUSION: The combined use of APC with the internal limiting membrane flap is advantageous because the APC acts to hold the internal limiting membrane in proper position and promotes the proliferation of glial cells through the presence of growth factors. This technique may be particularly advantageous in chronic or recalcitrant holes particularly in the setting of trauma.
PURPOSE: To describe a case of a large, traumatic macular hole in a pediatric patient closed using an internal limiting membrane flap in combination with autologous plasma concentrate (APC). METHODS: Description of a surgical technique as performed in one patient. RESULTS: Successful macular hole closure and improvement in postoperative visual acuity were achieved in the patient in whom the technique was performed. CONCLUSION: The combined use of APC with the internal limiting membrane flap is advantageous because the APC acts to hold the internal limiting membrane in proper position and promotes the proliferation of glial cells through the presence of growth factors. This technique may be particularly advantageous in chronic or recalcitrant holes particularly in the setting of trauma.
Authors: R N Johnson; H R McDonald; H Lewis; M G Grand; T G Murray; W F Mieler; M W Johnson; H C Boldt; K R Olsen; P E Tornambe; J C Folk Journal: Ophthalmology Date: 2001-05 Impact factor: 12.079
Authors: John B Miller; Yoshihiro Yonekawa; Dean Eliott; Ivana K Kim; Leo A Kim; John I Loewenstein; Lucia Sobrin; Lucy H Young; Shizuo Mukai; Demetrios G Vavvas Journal: Am J Ophthalmol Date: 2015-09-21 Impact factor: 5.258