Literature DB >> 2997859

High-affinity angiotensin receptors in rat adrenal medulla.

A Israel, M Niwa, L M Plunkett, J M Saavedra.   

Abstract

Angiotensin II receptors have been quantitated in single rat adrenal medullas by incubation of tissue sections with 125I-[Sar1]-AII, autoradiography with exposure to 3H-sensitive Ultrofilm, computerized densitometry and comparison with 125I-labelled standards. Rat adrenal medulla contains a single class of high affinity AII receptors with a Ka of 0.84 +/- 0.02 X 10(9) M-1 and a Bmax of 3259 +/- 502 fmol/mg protein, one of the highest densities in AII receptors found in rat tissues. These observations provide evidence for a local site of action of AII in the release of adrenal medullary catecholamines.

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Year:  1985        PMID： 2997859     DOI： 10.1016/0167-0115(85)90055-2

Source DB:  PubMed          Journal:  Regul Pept        ISSN： 0167-0115


  4 in total

Review 1.  Angiotensin II AT2 Receptors Contribute to Regulate the Sympathoadrenal and Hormonal Reaction to Stress Stimuli.

Authors:  J M Saavedra; I Armando
Journal:  Cell Mol Neurobiol       Date:  2017-09-07       Impact factor: 5.046

2.  Angiotensin-converting enzyme labeled with [3H]captopril. Tissue localizations and changes in different models of hypertension in the rat.

Authors:  S K Wilson; D R Lynch; S H Snyder
Journal:  J Clin Invest       Date:  1987-09       Impact factor: 14.808

3.  Atrial natriuretic factor receptors in rat kidney, adrenal gland, and brain: autoradiographic localization and fluid balance dependent changes.

Authors:  D R Lynch; K M Braas; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1986-05       Impact factor: 11.205

4.  Localization of binding sites for atrial natriuretic factor and angiotensin II in the central nervous system of the clawed toad Xenopus laevis.

Authors:  W Kloas; W Hanke
Journal:  Cell Tissue Res       Date:  1992-02       Impact factor: 5.249
  4 in total

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