Literature DB >> 2997737

Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3"(9)-O-nucleotidyltransferase.

M E Fling, J Kopf, C Richards.   

Abstract

The nucleotide sequence of a transposon Tn7 DNA fragment encoding a 3"(9)-O-nucleotidyltransferase, an aminoglycoside-modifying enzyme, which mediates bacterial resistance to spectinomycin and streptomycin, was determined. The aadA structural gene was 786 bases long and predicted a polypeptide of 262 amino acids with a calculated molecular weight of 29,207. Comparison of the DNA sequences of Tn7 and plasmid R538-1 indicated that their aadA genes were nearly identical. Comparison of the polypeptides predicted by the aadA genes of Tn7 and Tn554 indicated that the genes were related.

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Year:  1985        PMID： 2997737      PMCID： PMC322025          DOI： 10.1093/nar/13.19.7095

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  28 in total

1.  Analytical isoelectric focusing of R factor-determined beta-lactamases: correlation with plasmid compatibility.

Authors:  M Matthew; R W Hedges
Journal:  J Bacteriol       Date:  1976-02       Impact factor: 3.490

Review 2.  Regulatory sequences involved in the promotion and termination of RNA transcription.

Authors:  M Rosenberg; D Court
Journal:  Annu Rev Genet       Date:  1979       Impact factor: 16.830

3.  Enzymes that inactivate antibiotics in transit to their targets.

Authors:  J E Davies; R E Benveniste
Journal:  Ann N Y Acad Sci       Date:  1974-05-10       Impact factor: 5.691

4.  Transposition of a deoxyribonucleic acid sequence encoding trimethoprim and streptomycin resistances from R483 to other replicons.

Authors:  P T Barth; N Datta; R W Hedges; N J Grinter
Journal:  J Bacteriol       Date:  1976-03       Impact factor: 3.490

5.  Development of a DNA probe for the structural gene of the 2"-O-adenyltransferase aminoglycoside-modifying enzyme.

Authors:  F C Tenover; T D Gootz; K P Gordon; L S Tompkins; S A Young; J J Plorde
Journal:  J Infect Dis       Date:  1984-11       Impact factor: 5.226

6.  Nucleotide sequence of a streptomycete aminoglycoside phosphotransferase gene and its relationship to phosphotransferases encoded by resistance plasmids.

Authors:  C J Thompson; G S Gray
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

7.  Nucleotide sequence of the Streptococcus faecalis plasmid gene encoding the 3'5"-aminoglycoside phosphotransferase type III.

Authors:  P Trieu-Cuot; P Courvalin
Journal:  Gene       Date:  1983-09       Impact factor: 3.688

8.  The nucleotide sequence of the trimethoprim-resistant dihydrofolate reductase gene harbored by Tn7.

Authors:  M E Fling; C Richards
Journal:  Nucleic Acids Res       Date:  1983-08-11       Impact factor: 16.971

9.  Protein expression in Escherichia coli minicells containing recombinant plasmids specifying trimethoprim-resistant dihydrofolate reductases.

Authors:  M E Fling; L P Elwell
Journal:  J Bacteriol       Date:  1980-02       Impact factor: 3.490

10.  A system for shotgun DNA sequencing.

Authors:  J Messing; R Crea; P H Seeburg
Journal:  Nucleic Acids Res       Date:  1981-01-24       Impact factor: 16.971
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  37 in total

1.  Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli.

Authors:  D Sandvang
Journal:  Antimicrob Agents Chemother       Date:  1999-12       Impact factor: 5.191

2.  New gene cassettes for trimethoprim resistance, dfr13, and Streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron.

Authors:  P V Adrian; C J Thomson; K P Klugman; S G Amyes
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

3.  Development of a DNA probe from the deoxyribonucleotide sequence of a 3-N-aminoglycoside acetyltransferase [AAC(3)-I] resistance gene.

Authors:  F C Tenover; K L Phillips; T Gilbert; P Lockhart; P J O'Hara; J J Plorde
Journal:  Antimicrob Agents Chemother       Date:  1989-04       Impact factor: 5.191

4.  Sequence requirements of Escherichia coli attTn7, a specific site of transposon Tn7 insertion.

Authors:  R L McKown; K A Orle; T Chen; N L Craig
Journal:  J Bacteriol       Date:  1988-01       Impact factor: 3.490

5.  Highly efficient integration of foreign DNA into the genome of the green sulfur bacterium,Chlorobium vibrioforme by homologous recombination.

Authors:  S Kjærulff; D B Diep; J S Okkels; H V Scheller; J G Ormerod
Journal:  Photosynth Res       Date:  1994-07       Impact factor: 3.573

6.  Detection of a streptomycin/spectinomycin adenylyltransferase gene (aadA) in Enterococcus faecalis.

Authors:  N C Clark; O Olsvik; J M Swenson; C A Spiegel; F C Tenover
Journal:  Antimicrob Agents Chemother       Date:  1999-01       Impact factor: 5.191

7.  The dhfrI trimethoprim resistance gene of Tn7 can be found at specific sites in other genetic surroundings.

Authors:  L Sundström; O Sköld
Journal:  Antimicrob Agents Chemother       Date:  1990-04       Impact factor: 5.191

8.  Bacterial transposon Tn7 utilizes two different classes of target sites.

Authors:  K M Kubo; N L Craig
Journal:  J Bacteriol       Date:  1990-05       Impact factor: 3.490

9.  On the evolution of Tn21-like multiresistance transposons: sequence analysis of the gene (aacC1) for gentamicin acetyltransferase-3-I(AAC(3)-I), another member of the Tn21-based expression cassette.

Authors:  W Wohlleben; W Arnold; L Bissonnette; A Pelletier; A Tanguay; P H Roy; G C Gamboa; G F Barry; E Aubert; J Davies
Journal:  Mol Gen Genet       Date:  1989-06

10.  Characterization of an insertion sequence (IS891) of novel structure from the cyanobacterium Anabaena sp. strain M-131.

Authors:  I Bancroft; C P Wolk
Journal:  J Bacteriol       Date:  1989-11       Impact factor: 3.490
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