| Literature DB >> 29976979 |
Dewu Zhang1, Jianyuan Zhao1, Xinwei Wang1, Lili Zhao1, Hongyu Liu1, Yuzhen Wei1, Xuefu You1, Shan Cen1, Liyan Yu2.
Abstract
A new azaphilone derivative, named peniazaphilin A (1) and one known isocoumarin, (R)-3-methyl-6-hydroxy-8-methoxy-3,4-dihydroisocoumarin (2) were isolated from the fungus Penicillium sp. CPCC 400786. Their structures were elucidated by means of extensive spectroscopic analysis. The absolute configuration of 2 was established by circular dichroism for the first time. Compounds 1 and 2 exhibited weak anti-HIV activities with the IC50 values of 60.4 and 69.3 μM, respectively.Entities:
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Year: 2018 PMID： 29976979 DOI： 10.1038/s41429-018-0077-4
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649