Laura E Donovan1, Mary R Welch2. 1. The Neurological Institute of New York, 710 West 168th St, New York, NY, 10032, USA. 2. The Neurological Institute of New York, 710 West 168th St, New York, NY, 10032, USA. mw2517@cumc.columbia.edu.
Abstract
PURPOSE OF REVIEW: Pituitary tumors account for approximately 17% of all intracranial neoplasms, with the majority being pituitary adenomas. Often, these are found incidentally during a workup for headache; however, the relationship between symptom and pathology remains unclear. The purpose of this article is to review the most recent literature on the epidemiology, pathophysiology, and management of headaches in patients with pituitary tumors. RECENT FINDINGS: The current literature is limited, with few prospective trials focusing on this question. With the exception of pituitary apoplexy, the relationship between headaches and pituitary masses remains unclear. Intervention does not always improve headache and can lead to development of new headache syndromes. Further research is needed to better elucidate the relationship between pituitary tumors and headaches. Headache alone is rarely an indication for surgical management of a pituitary adenoma.
PURPOSE OF REVIEW: Pituitary tumors account for approximately 17% of all intracranial neoplasms, with the majority being pituitary adenomas. Often, these are found incidentally during a workup for headache; however, the relationship between symptom and pathology remains unclear. The purpose of this article is to review the most recent literature on the epidemiology, pathophysiology, and management of headaches in patients with pituitary tumors. RECENT FINDINGS: The current literature is limited, with few prospective trials focusing on this question. With the exception of pituitary apoplexy, the relationship between headaches and pituitary masses remains unclear. Intervention does not always improve headache and can lead to development of new headache syndromes. Further research is needed to better elucidate the relationship between pituitary tumors and headaches. Headache alone is rarely an indication for surgical management of a pituitary adenoma.
Authors: Arman Jahangiri; Jeffrey R Wagner; Aaron T Chin; Sung Won Han; Mai T Tran; Liane M Miller; Maxwell W Tom; Rebecca Chen; Sandeep Kunwar; Lewis Blevins; Manish K Aghi Journal: Clin Neurol Neurosurg Date: 2015-02-20 Impact factor: 1.876
Authors: Domenico Solari; Luigi Maria Cavallo; Teresa Somma; Carmela Chiaramonte; Felice Esposito; Marialaura Del Basso De Caro; Paolo Cappabianca Journal: PLoS One Date: 2015-10-16 Impact factor: 3.240
Authors: Wouter R van Furth; Amir H Zamanipoor Najafabadi; Merel van der Meulen; Marco J T Verstegen; Daniel J Lobatto; Maarten C Kleijwegt; Alberto M Pereira; Nienke R Biermasz Journal: Pituitary Date: 2022-01-10 Impact factor: 4.107
Authors: Agnes Andersson; Tobias Hallén; Daniel S Olsson; Dan Farahmand; Ann-Charlotte Olofsson; Eva Jakobsson Ung; Sofie Jakobsson; Henrik Bergquist; Gudmundur Johannsson; Oskar Ragnarsson; Thomas Skoglund Journal: J Neurol Surg B Skull Base Date: 2021-05-29