Literature DB >> 29972350

A clinical isolate of Escherichia coli co-harbouring mcr-1 and blaNDM-5 in Japan.

Hiroki Uchida1, Tatsuya Tada1, Yoshie Sugahara2, Akira Kato3, Isao Miyairi4,5, Teruo Kirikae1.   

Abstract

The mcr-1 gene encodes a phosphoethanolamine transferase, which confers resistance to colistin by transferring phosphoethanolamine to lipid A. This study describes the emergence of a colistin- and carbapenem-resistant clinical isolate of Escherichia coli harbouring mcr-1 and blaNDM-5 genes, located on 90 and 150 Kb plasmids, respectively. The isolate belonged to ST132. This is the first report of a clinical isolate in Japan co-harbouring mcr-1 and blaNDM-5.

Entities:  

Keywords:  CRE; Mcr-1; NDM-5; colistin resistance

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Year:  2018        PMID： 29972350     DOI： 10.1099/jmm.0.000793

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN： 0022-2615            Impact factor:   2.472


  3 in total

1.  Addition of L-cysteine to the N- or C-terminus of the all-D-enantiomer [D(KLAKLAK)2] increases antimicrobial activities against multidrug-resistant Pseudomonas aeruginosa, Acinetobacter baumannii and Escherichia coli.

Authors:  Maki K Ohno; Isao Ishida; Teruo Kirikae; Eisaku Yoshihara; Fumiko Kirikae
Journal:  PeerJ       Date:  2020-11-30       Impact factor: 2.984

2.  blaNDM and mcr-1 to mcr-5 Gene Distribution Characteristics in Gut Specimens from Different Regions of China.

Authors:  Dongyue Lv; Ran Duan; Rong Fan; Hui Mu; Junrong Liang; Meng Xiao; Zhaokai He; Shuai Qin; Jinchuan Yang; Huaiqi Jing; Zhaoguo Wang; Xin Wang
Journal:  Antibiotics (Basel)       Date:  2021-02-25

3.  Characterization of the IncFII-IncFIB(pB171) Plasmid Carrying bla NDM-5 in Escherichia coli ST405 Clinical Isolate in Japan.

Authors:  Yoko Takayama; Tsuyoshi Sekizuka; Hidehito Matsui; Yuzuru Adachi; Ryotaro Eda; Shin Nihonyanagi; Tatsuhiko Wada; Mari Matsui; Satowa Suzuki; Masashi Takaso; Hidero Kitasato; Makoto Kuroda; Hideaki Hanaki
Journal:  Infect Drug Resist       Date:  2020-02-18       Impact factor: 4.003
  3 in total

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