Christian Mehl1, Matthias Kern1, Friederike Neumann1, Telse Bähr2, Jörg Wiltfang3, Volker Gassling3. 1. Department of Prosthodontics, Propaedeutics and Dental Materials, Christian-Albrechts University at Kiel, Arnold-Heller-Straße 16, 24105, Kiel, Germany. 2. Private Practice, Lassabeker Weg 3, 24211, Lehmkuhlen, Germany. 3. Department of Oral and Maxillofacial Surgery, Christian-Albrechts University at Kiel, Arnold-Heller-Straße 16, 24105, Kiel, Germany.
Abstract
OBJECTIVE: The aim of the current study was to evaluate the effect of ultraviolet (UV) photofunctionalization of dental titanium implants with exposure to the oral cavity on osseointegration in an animal model. METHODS: Forty-eight titanium implants (Camlog® Conelog® 4.3 mmx9.0 mm) were placed epicrestally into the edentulous jaws of three minipigs and implant stability was assessed by measuring the implant stability quotient (ISQ). Prior to implantation half of the implants were photofunctionalized with intense UV-light. After three months, the implants were exposed and ISQ was measured again. After six months of implant exposure, the minipigs were sacrificed and the harvested specimens were analyzed using histomorphometric, light, and fluorescence microscopy. MAIN RESULTS: Forty-two of 48 implants osseointegrated. The overall mean bone-implant contact area (BIC) was (64±22)%. No significant differences were found in BIC or ISQ value (multivariate analysis of variance (MANOVA), P>0.05) between implants with and without exposure to UV photofunctionalization. CONCLUSIONS: No significant effects were observed on osseointegration of dental titanium implants nine months after exposure of UV photofunctionalization.
OBJECTIVE: The aim of the current study was to evaluate the effect of ultraviolet (UV) photofunctionalization of dental titanium implants with exposure to the oral cavity on osseointegration in an animal model. METHODS: Forty-eight titanium implants (Camlog® Conelog® 4.3 mmx9.0 mm) were placed epicrestally into the edentulous jaws of three minipigs and implant stability was assessed by measuring the implant stability quotient (ISQ). Prior to implantation half of the implants were photofunctionalized with intense UV-light. After three months, the implants were exposed and ISQ was measured again. After six months of implant exposure, the minipigs were sacrificed and the harvested specimens were analyzed using histomorphometric, light, and fluorescence microscopy. MAIN RESULTS: Forty-two of 48 implants osseointegrated. The overall mean bone-implant contact area (BIC) was (64±22)%. No significant differences were found in BIC or ISQ value (multivariate analysis of variance (MANOVA), P>0.05) between implants with and without exposure to UV photofunctionalization. CONCLUSIONS: No significant effects were observed on osseointegration of dental titanium implants nine months after exposure of UV photofunctionalization.
Authors: Tiziano Tealdo; Marco Bevilacqua; Francesco Pera; Maria Menini; Giambattista Ravera; Carl Drago; Paolo Pera Journal: J Prosthet Dent Date: 2008-05 Impact factor: 3.426
Authors: Stephan T Becker; Hendrik Bolte; Oliver Krapf; Hermann Seitz; Timothy Douglas; Sureshan Sivananthan; Jörg Wiltfang; Eugene Sherry; Patrick H Warnke Journal: Oral Oncol Date: 2009-08-31 Impact factor: 5.337