Literature DB >> 29970935

Self-Monitoring of Fertility Hormones: A New Era for Natural Family Planning?

Leonard Blackwell1,2, Delwyn Cooke1,2, Simon Brown3,4.   

Abstract

Natural family planning (NFP) methods have served many generations well, and in particular, the symptothermal or symptohormonal methods. The comparison of daily mucus and temperature records for individual cycles with daily hormone measurements, which is now possible, shows that some of the assumptions underlying NFP may not be completely accurate. The various methods are inadvertently depending on an element of chance, which, of course, cannot be known by the NFP user. However, it is statistically inevitable that such errors will result eventually in an unexpected pregnancy, and these discrepancies are the likely reason for the method failures. Further research and integration of home hormone measurements with NFP symptoms are needed. Summary: Traditional NFP methods, based on the observations of temperature, mucus, and luteinizing hormone, can work well. However, these data are sometimes difficult to interpret, and significant changes in the variables are sometimes "missing" from some cycles. Changes in these variables are elicited by the estrogen and progesterone released from the ovaries. It follows that the direct measures of events in the ovaries are the levels of estrogen and progesterone or their derivatives in blood or urine. Measurements of urinary derivatives of estrogen and progesterone can be used to monitor the ovaries directly and are clearer indicators than traditional NFP methods.

Entities:  

Keywords:  natural family planning; self-monitoring; urinary hormones

Year:  2018        PMID: 29970935      PMCID: PMC6027114          DOI: 10.1177/0024363918756387

Source DB:  PubMed          Journal:  Linacre Q        ISSN: 0024-3639


  43 in total

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Journal:  Reprod Toxicol       Date:  1992       Impact factor: 3.143

2.  Relationship of serum estradiol and progesterone concentrations to the excretion profiles of their major urinary metabolites as measured by enzyme immunoassay and radioimmunoassay.

Authors:  C J Munro; G H Stabenfeldt; J R Cragun; L A Addiego; J W Overstreet; B L Lasley
Journal:  Clin Chem       Date:  1991-06       Impact factor: 8.327

3.  Variability in the hormonally estimated fertile phase of the menstrual cycle.

Authors:  Richard J Fehring; Mary Schneider
Journal:  Fertil Steril       Date:  2008-02-04       Impact factor: 7.329

4.  Hormonal monitoring of ovarian activity using the Ovarian Monitor, part I. Validation of home and laboratory results obtained during ovulatory cycles by comparison with radioimmunoassay.

Authors:  Leonard F Blackwell; James B Brown; Pilar Vigil; Barbara Gross; Saulat Sufi; Catherine d'Arcangues
Journal:  Steroids       Date:  2003-05       Impact factor: 2.668

5.  Monitoring of ovarian activity by daily measurement of urinary excretion rates of oestrone glucuronide and pregnanediol glucuronide using the Ovarian Monitor, Part III: variability of normal menstrual cycle profiles.

Authors:  Leonard F Blackwell; Pilar Vigil; Delwyn G Cooke; Catherine d'Arcangues; James B Brown
Journal:  Hum Reprod       Date:  2013-10-29       Impact factor: 6.918

6.  Prediction of ovarian cycle outcome by follicular characteristics, stage 1.

Authors:  M A Gore; P L Nayudu; V Vlaisavljevic; N Thomas
Journal:  Hum Reprod       Date:  1995-09       Impact factor: 6.918

7.  Mean versus individual hormonal profiles in the menstrual cycle.

Authors:  María Elena Alliende
Journal:  Fertil Steril       Date:  2002-07       Impact factor: 7.329

8.  Comparison of a rapid, quantitative and automated assay for urinary luteinizing hormone (LH), with an LH detection test, for the prediction of ovulation.

Authors:  P Bischof; P G Bianchi; A Campana
Journal:  Hum Reprod       Date:  1991-04       Impact factor: 6.918

9.  Ultrasonic observation of the mechanism of human ovulation.

Authors:  L C de Crespigny; C O'Herlihy; H P Robinson
Journal:  Am J Obstet Gynecol       Date:  1981-03-15       Impact factor: 8.661

10.  Monitoring of ovarian activity by measurement of urinary excretion rates using the Ovarian Monitor, Part IV: the relationship of the pregnanediol glucuronide threshold to basal body temperature and cervical mucus as markers for the beginning of the post-ovulatory infertile period.

Authors:  Leonard F Blackwell; Pilar Vigil; María Elena Alliende; Simon Brown; Mario Festin; Delwyn G Cooke
Journal:  Hum Reprod       Date:  2015-12-17       Impact factor: 6.918

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  2 in total

1.  The Fertility Indicator Equation Using Serum Progesterone and Urinary Pregnanediol-3-Glucuronide for Assessment of Ovulatory to Luteal Phase Transition.

Authors:  Stephen J Usala; María Elena Alliende; A Alexandre Trindade
Journal:  Medicina (Kaunas)       Date:  2021-02-03       Impact factor: 2.430

2.  A Novel Fertility Indicator Equation Using Estradiol Levels for Assessment of Phase of the Menstrual Cycle.

Authors:  Stephen J Usala; A Alexandre Trindade
Journal:  Medicina (Kaunas)       Date:  2020-10-22       Impact factor: 2.430

  2 in total

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