| Literature DB >> 29967912 |
Maria Ejlersen1, Chenguang Lou, Yogesh S Sanghvi, Yitzhak Tor, Jesper Wengel.
Abstract
The on-column functionalization of oligodeoxynucleotides via base-free Suzuki cross-coupling reactions is reported herein. These cross-coupling reactions were carried out with various boronic acids and either full-length modified oligonucleotides containing one or more 2'-deoxy-5-iodouridine (5IdU) monomer(s) or on oligonucleotide fragments immediately after incorporation of 5IdU. Five different functionalities were coupled to oligonucleotides containing one or three attachment points.Entities:
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Year: 2018 PMID： 29967912 DOI： 10.1039/c8cc01360h
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222