Literature DB >> 29967845

The Pitfalls of Febrile Jaundice. A Case Report.

Maria Obreja1, Andra Teodor1,2, Daniela Leca1,2, Alexandr Ceasovschih3, Egidia Miftode1,2.   

Abstract

Jaundice in sepsis is usually caused by cholestasis, and its onset can precede other manifestations of the infection. Inflammation-induced cholestasis is a common complication in patients with an extrahepatic infection or those with inflammatory processes. We describe the case of a 47 years old female who presented with low back pain and paravertebral muscular contracture. She subsequently developed a cholestatic syndrome with clinical manifestations such as jaundice, followed by fever and sepsis with multiple organ dysfunction. Initially labeled as biliary sepsis, the diagnosis was crucially reoriented as the blood cultures were positive for Streptococcus pyogenes and the magnetic resonance imaging (MRI) findings suggested spondylodiscitis as well as a paravertebral abscess.

Entities:  

Keywords:  S.pyogenes; blood cultures; fever; jaundice; lower back pain; sepsis

Year:  2016        PMID: 29967845      PMCID: PMC5939134          DOI: 10.1515/jccm-2016-0013

Source DB:  PubMed          Journal:  J Crit Care Med (Targu Mures)        ISSN: 2393-1817


  9 in total

Review 1.  Sepsis-induced cholestasis.

Authors:  Nisha Chand; Arun J Sanyal
Journal:  Hepatology       Date:  2007-01       Impact factor: 17.425

2.  The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Authors:  Mervyn Singer; Clifford S Deutschman; Christopher Warren Seymour; Manu Shankar-Hari; Djillali Annane; Michael Bauer; Rinaldo Bellomo; Gordon R Bernard; Jean-Daniel Chiche; Craig M Coopersmith; Richard S Hotchkiss; Mitchell M Levy; John C Marshall; Greg S Martin; Steven M Opal; Gordon D Rubenfeld; Tom van der Poll; Jean-Louis Vincent; Derek C Angus
Journal:  JAMA       Date:  2016-02-23       Impact factor: 56.272

3.  Sepsis-associated cholestasis.

Authors:  R H Moseley
Journal:  Gastroenterology       Date:  1997-01       Impact factor: 22.682

Review 4.  The role of inflammation in cholestasis: clinical and basic aspects.

Authors:  Astrid Kosters; Saul J Karpen
Journal:  Semin Liver Dis       Date:  2010-04-26       Impact factor: 6.115

5.  Biopsy for suspected spondylodiscitis.

Authors:  A Gasbarrini; L Boriani; C Salvadori; S Mobarec; J Kreshak; C Nanni; E Zamparini; M Alberghini; P Viale; U Albisinni
Journal:  Eur Rev Med Pharmacol Sci       Date:  2012-04       Impact factor: 3.507

6.  The changing epidemiology of bacteraemic osteoarticular infections in the early 21st century.

Authors:  O Murillo; I Grau; J Lora-Tamayo; J Gomez-Junyent; A Ribera; F Tubau; J Ariza; R Pallares
Journal:  Clin Microbiol Infect       Date:  2014-10-12       Impact factor: 8.067

Review 7.  Spinal infection: state of the art and management algorithm.

Authors:  Rui M Duarte; Alexander R Vaccaro
Journal:  Eur Spine J       Date:  2013-06-12       Impact factor: 3.134

Review 8.  Atypical causes of cholestasis.

Authors:  Ken D Nguyen; Vinay Sundaram; Walid S Ayoub
Journal:  World J Gastroenterol       Date:  2014-07-28       Impact factor: 5.742

Review 9.  Clinical review: The liver in sepsis.

Authors:  Nicolas Nesseler; Yoann Launey; Caroline Aninat; Fabrice Morel; Yannick Mallédant; Philippe Seguin
Journal:  Crit Care       Date:  2012-10-30       Impact factor: 9.097

  9 in total
  1 in total

Review 1.  Pathophysiology of sepsis-induced cholestasis: A review.

Authors:  Maria Iuliana Ghenu; Dorin Dragoş; Maria Mirabela Manea; Dorin Ionescu; Lucian Negreanu
Journal:  JGH Open       Date:  2022-05-25
  1 in total

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