Literature DB >> 29967225

Synergistic inactivation of AXL: a (cross)road to cure ovarian cancer?

Chiara Zurzolo1.   

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Year:  2018        PMID: 29967225      PMCID: PMC6073200          DOI: 10.15252/embr.201846492

Source DB:  PubMed          Journal:  EMBO Rep        ISSN: 1469-221X            Impact factor:   8.807


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  9 in total

1.  The Tumor-Suppressor Protein OPCML Potentiates Anti-EGFR- and Anti-HER2-Targeted Therapy in HER2-Positive Ovarian and Breast Cancer.

Authors:  Elisa Zanini; Louay S Louis; Jane Antony; Evdoxia Karali; Imoh S Okon; Arthur B McKie; Sebastian Vaughan; Mona El-Bahrawy; Justin Stebbing; Chiara Recchi; Hani Gabra
Journal:  Mol Cancer Ther       Date:  2017-08-03       Impact factor: 6.261

2.  AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas.

Authors:  Moshe Elkabets; Evangelos Pazarentzos; Dejan Juric; Qing Sheng; Raphael A Pelossof; Samuel Brook; Ana Oaknin Benzaken; Jordi Rodon; Natasha Morse; Jenny Jiacheng Yan; Manway Liu; Rita Das; Yan Chen; Angela Tam; Huiqin Wang; Jinsheng Liang; Joseph M Gurski; Darcy A Kerr; Rafael Rosell; Cristina Teixidó; Alan Huang; Ronald A Ghossein; Neal Rosen; Trever G Bivona; Maurizio Scaltriti; José Baselga
Journal:  Cancer Cell       Date:  2015-04-13       Impact factor: 31.743

3.  Targeting the AXL signaling pathway in ovarian cancer.

Authors:  Ruby Yun-Ju Huang; Jane Antony; Tuan Zea Tan; David Shao-Peng Tan
Journal:  Mol Cell Oncol       Date:  2016-11-28

Review 4.  AXL-Driven EMT State as a Targetable Conduit in Cancer.

Authors:  Jane Antony; Ruby Yun-Ju Huang
Journal:  Cancer Res       Date:  2017-06-30       Impact factor: 12.701

5.  The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer.

Authors:  Jane Antony; Tuan Zea Tan; Zoe Kelly; Jeffrey Low; Mahesh Choolani; Chiara Recchi; Hani Gabra; Jean Paul Thiery; Ruby Yun-Ju Huang
Journal:  Sci Signal       Date:  2016-10-04       Impact factor: 8.192

6.  Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21.

Authors:  S LaForgia; B Morse; J Levy; G Barnea; L A Cannizzaro; F Li; P C Nowell; L Boghosian-Sell; J Glick; A Weston
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-01       Impact factor: 11.205

Review 7.  Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer.

Authors:  David D Bowtell; Steffen Böhm; Ahmed A Ahmed; Paul-Joseph Aspuria; Robert C Bast; Valerie Beral; Jonathan S Berek; Michael J Birrer; Sarah Blagden; Michael A Bookman; James D Brenton; Katherine B Chiappinelli; Filipe Correia Martins; George Coukos; Ronny Drapkin; Richard Edmondson; Christina Fotopoulou; Hani Gabra; Jérôme Galon; Charlie Gourley; Valerie Heong; David G Huntsman; Marcin Iwanicki; Beth Y Karlan; Allyson Kaye; Ernst Lengyel; Douglas A Levine; Karen H Lu; Iain A McNeish; Usha Menon; Steven A Narod; Brad H Nelson; Kenneth P Nephew; Paul Pharoah; Daniel J Powell; Pilar Ramos; Iris L Romero; Clare L Scott; Anil K Sood; Euan A Stronach; Frances R Balkwill
Journal:  Nat Rev Cancer       Date:  2015-11       Impact factor: 60.716

8.  The OPCML tumor suppressor functions as a cell surface repressor-adaptor, negatively regulating receptor tyrosine kinases in epithelial ovarian cancer.

Authors:  Arthur B McKie; Sebastian Vaughan; Elisa Zanini; Imoh S Okon; Louay Louis; Camila de Sousa; Mark I Greene; Qiang Wang; Roshan Agarwal; Dmitry Shaposhnikov; Joshua L C Wong; Hatice Gungor; Szymon Janczar; Mona El-Bahrawy; Eric W-F Lam; Naomi E Chayen; Hani Gabra
Journal:  Cancer Discov       Date:  2012-02       Impact factor: 39.397

9.  Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer.

Authors:  Tuan Zea Tan; Qing Hao Miow; Ruby Yun-Ju Huang; Meng Kang Wong; Jieru Ye; Jieying Amelia Lau; Meng Chu Wu; Luqman Hakim Bin Abdul Hadi; Richie Soong; Mahesh Choolani; Ben Davidson; Jahn M Nesland; Ling-Zhi Wang; Noriomi Matsumura; Masaki Mandai; Ikuo Konishi; Boon-Cher Goh; Jeffrey T Chang; Jean Paul Thiery; Seiichi Mori
Journal:  EMBO Mol Med       Date:  2013-05-13       Impact factor: 12.137

  9 in total
  2 in total

Review 1.  Applications of the Chick Chorioallantoic Membrane as an Alternative Model for Cancer Studies.

Authors:  Pei-Yu Chu; Angele Pei-Fern Koh; Jane Antony; Ruby Yun-Ju Huang
Journal:  Cells Tissues Organs       Date:  2021-03-29       Impact factor: 2.208

Review 2.  The Role of the Tumor Suppressor Gene Protein Tyrosine Phosphatase Gamma in Cancer.

Authors:  Christian Boni; Claudio Sorio
Journal:  Front Cell Dev Biol       Date:  2022-01-05
  2 in total

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