Literature DB >> 2996711

Neuropeptide Y reduces orthodromically evoked population spike in rat hippocampal CA1 by a possibly presynaptic mechanism.

W F Colmers, K Lukowiak, Q J Pittman.   

Abstract

Application of the brain neuropeptide Y (NPY) to rat hippocampus in vitro reversibly reduced the amplitude of the CA1 population spike evoked by stratum radiatum stimulation. Threshold for the effect was 10(-8) M. NPY had similar effects on single pulse- and paired pulse-evoked population spikes. Antidromic population spikes, evoked from the alveus, were unaffected by NPY. Thus, NPY appears to modulate excitatory transmission in the hippocampus by a presynaptic mechanism.

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Year:  1985        PMID： 2996711     DOI： 10.1016/0006-8993(85)90880-7

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  16 in total

1.  Presynaptic action of neuropeptide Y in area CA1 of the rat hippocampal slice.

Authors:  W F Colmers; K Lukowiak; Q J Pittman
Journal:  J Physiol       Date:  1987-02       Impact factor: 5.182

2.  Presynaptic inhibition by neuropeptide Y in rat hippocampal slice in vitro is mediated by a Y2 receptor.

Authors:  W F Colmers; G J Klapstein; A Fournier; S St-Pierre; K A Treherne
Journal:  Br J Pharmacol       Date:  1991-01       Impact factor: 8.739

3.  Somatostatin inhibits excitatory transmission at rat hippocampal synapses via presynaptic receptors.

Authors:  S Boehm; H Betz
Journal:  J Neurosci       Date:  1997-06-01       Impact factor: 6.167

4.  Tyrosine hydroxylase- and neuropeptide Y-immunoreactive nerve fibers in the pineal complex of untreated rats and rats following removal of the superior cervical ganglia.

Authors:  E T Zhang; J D Mikkelsen; M Møller
Journal:  Cell Tissue Res       Date:  1991-07       Impact factor: 5.249

5.  Neuropeptide Y reduces the expression of PLCB2, PLCD1 and selected PLC genes in cultured human endothelial cells.

Authors:  V R Lo Vasco; M Leopizzi; C Puggioni; C Della Rocca; R Businaro
Journal:  Mol Cell Biochem       Date:  2014-06-06       Impact factor: 3.396

6.  Investigations into neuropeptide Y-mediated presynaptic inhibition in cultured hippocampal neurones of the rat.

Authors:  D Bleakman; N L Harrison; W F Colmers; R J Miller
Journal:  Br J Pharmacol       Date:  1992-10       Impact factor: 8.739

7.  Effects of centrally administered neuropeptide Y (NPY) and NPY13-36 on the brain monoaminergic systems of the rat.

Authors:  M Heilig; L Vècséi; C Wahlestedt; C Alling; E Widerlöv
Journal:  J Neural Transm Gen Sect       Date:  1990

8.  Central neuropeptide Y and the sigma ligand, JO 1784, reverse corticotropin-releasing factor-induced inhibition of gastric acid secretion in rats.

Authors:  M Gué; M Yoneda; H Mönnikes; J L Junien; Y Taché
Journal:  Br J Pharmacol       Date:  1992-11       Impact factor: 8.739

9.  Neuropeptide Y inhibits potassium-stimulated glutamate release through Y2 receptors in rat hippocampal slices in vitro.

Authors:  S Greber; C Schwarzer; G Sperk
Journal:  Br J Pharmacol       Date:  1994-11       Impact factor: 8.739

10.  Blockade of neuropeptide Y(2) receptors and suppression of NPY's anti-epileptic actions in the rat hippocampal slice by BIIE0246.

Authors:  Bouchaïb El Bahh; Jeffrey Q Cao; Annette G Beck-Sickinger; William F Colmers
Journal:  Br J Pharmacol       Date:  2002-06       Impact factor: 8.739
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