Literature DB >> 29964079

Current state of in vivo panning technologies: Designing specificity and affinity into the future of drug targeting.

Heather H Gustafson1, Audrey Olshefsky2, Meilyn Sylvestre1, Drew L Sellers3, Suzie H Pun4.   

Abstract

Targeting ligands are used in drug delivery to improve drug distribution to desired cells or tissues and to facilitate cellular entry. In vivo biopanning, whereby billions of potential ligand sequences are screened in biologically-relevant and complex conditions, is a powerful method for identification of novel target ligands. This tool has impacted drug delivery technologies and expanded our arsenal of therapeutics and diagnostics. Within this review we will discuss current in vivo panning technologies and ways that these technologies can be improved to advance next-generation drug delivery strategies.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Aptamers; Biopanning; Drug delivery; In vivo; Peptides; Viral capsids

Mesh：

Substances：

Year:  2018        PMID： 29964079      PMCID： PMC6512807          DOI： 10.1016/j.addr.2018.06.015

Source DB:  PubMed          Journal:  Adv Drug Deliv Rev        ISSN： 0169-409X            Impact factor:   15.470


  123 in total

1.  Uptake and processing of modified bacteriophage M13 in mice: implications for phage display.

Authors:  Tom J M Molenaar; Ingrid Michon; Sonja A M de Haas; Theo J C van Berkel; Johan Kuiper; Erik A L Biessen
Journal:  Virology       Date:  2002-02-01       Impact factor: 3.616

2.  Phage antibodies: filamentous phage displaying antibody variable domains.

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Journal:  Nature       Date:  1990-12-06       Impact factor: 49.962

Review 3.  B cell repertoire and ageing.

Authors:  Deborah K Dunn-Walters; Alexander A Ademokun
Journal:  Curr Opin Immunol       Date:  2010-05-25       Impact factor: 7.486

4.  Directed evolution of adeno-associated virus (AAV) as vector for muscle gene therapy.

Authors:  Lin Yang; Juan Li; Xiao Xiao
Journal:  Methods Mol Biol       Date:  2011

5.  Organic additives stabilize RNA aptamer binding of malachite green.

Authors:  Yubin Zhou; Hong Chi; Yuanyuan Wu; Robert S Marks; Terry W J Steele
Journal:  Talanta       Date:  2016-07-01       Impact factor: 6.057

6.  In vivo phage display to identify new human antibody fragments homing to atherosclerotic endothelial and subendothelial tissues [corrected].

Authors:  Kamel Deramchia; Marie-Josée Jacobin-Valat; Amélie Vallet; Hervé Bazin; Xavier Santarelli; Stéphane Sanchez; Pierre Dos Santos; Jean-Michel Franconi; Stéphane Claverol; Stéphane Bonetto; Gisèle Clofent-Sanchez
Journal:  Am J Pathol       Date:  2012-04-17       Impact factor: 4.307

7.  Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma.

Authors:  Jason A Hoffman; Enrico Giraudo; Mallika Singh; Lianglin Zhang; Masahiro Inoue; Kimmo Porkka; Douglas Hanahan; Erkki Ruoslahti
Journal:  Cancer Cell       Date:  2003-11       Impact factor: 31.743

8.  A system for the continuous directed evolution of biomolecules.

Authors:  Kevin M Esvelt; Jacob C Carlson; David R Liu
Journal:  Nature       Date:  2011-04-10       Impact factor: 49.962

9.  The Rational Design of Therapeutic Peptides for Aminopeptidase N using a Substrate-Based Approach.

Authors:  Shilvi Joshi; Lang Chen; Michael B Winter; Yi-Lun Lin; Yang Yang; Mariya Shapovalova; Paige M Smith; Chang Liu; Fang Li; Aaron M LeBeau
Journal:  Sci Rep       Date:  2017-05-02       Impact factor: 4.379

10.  Ion-dependent conformational switching by a DNA aptamer that induces remyelination in a mouse model of multiple sclerosis.

Authors:  John Smestad; L James Maher
Journal:  Nucleic Acids Res       Date:  2012-11-21       Impact factor: 16.971
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  2 in total

Review 1.  Identification and characterization of adipose surface epitopes.

Authors:  Yasuhiro Onogi; Ahmed Elagamy Mohamed Mahmoud Khalil; Siegfried Ussar
Journal:  Biochem J       Date:  2020-07-17       Impact factor: 3.857

Review 2.  Rationally Designed DNA Nanostructures for Drug Delivery.

Authors:  Fan Xu; Qing Xia; Pengfei Wang
Journal:  Front Chem       Date:  2020-09-24       Impact factor: 5.221
  2 in total

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