| Literature DB >> 29963869 |
Rongkang Wang1, Lvqi Jiang1, Wenbin Yi1.
Abstract
Metal-free trifluoroethylthiolation with fluorinated sulfinate salt NaSO2CH2CF3 under reductive conditions has been developed. The strategy enables the installation of the SCH2CF3 moiety efficiently to form a number of unexplored stable trifluoroethylthiolated heterocycles, arenes, and thiols, which have the potential to be a new series of fluorine-containing chemical entities for medicinal chemists.Entities:
Year: 2018 PMID： 29963869 DOI： 10.1021/acs.joc.8b00676
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354