Literature DB >> 29962458

Alkylated Benzoquinones: Quinquequinones A–H from the Leaves of Ardisia quinquegona and Their Anti-Leishmania Activity [corrected].

Shintaro Asaumi1, Susumu Kawakami2, Sachiko Sugimoto1, Katsuyoshi Matsunami1, Hideaki Otsuka1,2, Takakazu Shinzato3.   

Abstract

Eight alkylated benzoquinone derivatives, named ardisiaquinones A-H, were isolated together with four known compounds from the leaves of Ardisia quinquegona using a combination of different chromatography techniques. Their structures were elucidated by spectroscopy and by the preparation of methyl ethers. Anti-Leishmania activity and cytotoxicity of the isolated compounds were assayed. Some compounds showed moderate anti-Leishmania activity, however, always associated with cytotoxicity.

Entities:  

Keywords:  Ardisia quinquegona; Primulaceae; alkylated benzoquinone; anti-Leishmania activity

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Year:  2018        PMID: 29962458     DOI: 10.1248/cpb.c18-00281

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

Review 1.  Searching for constituents from plants in geographically characterized areas, Egypt, Madagascar, and Okinawa.

Authors:  Sachiko Sugimoto
Journal:  J Nat Med       Date:  2022-08-12       Impact factor: 3.192

  1 in total

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