Nour Zleik1,2, Mohanad M Elfishawi1,2, Zoran Kvrgic1,2, Clement J Michet1,2, Cynthia S Crowson3,4, Eric L Matteson1,2, Tim Bongartz1,2. 1. From the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA. 2. N. Zleik, MD, Rheumatology Fellow, Division of Rheumatology, Augusta University; M.M. Elfishawi, MD, Internal Medicine Resident, Icahn School of Medicine at Mount Sinai; Z. Kvrgic, CCRP, Study Coordinator, Mayo Clinic; C.J. Michet Jr., MD, Consultant, Mayo Clinic; C.S. Crowson, MS, Associate Professor, Mayo Clinic; E.L. Matteson, MD, MPH, Consultant, Mayo Clinic; T. Bongartz, MD, MS, Vanderbilt University. 3. From the Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA. crowson@mayo.edu. 4. N. Zleik, MD, Rheumatology Fellow, Division of Rheumatology, Augusta University; M.M. Elfishawi, MD, Internal Medicine Resident, Icahn School of Medicine at Mount Sinai; Z. Kvrgic, CCRP, Study Coordinator, Mayo Clinic; C.J. Michet Jr., MD, Consultant, Mayo Clinic; C.S. Crowson, MS, Associate Professor, Mayo Clinic; E.L. Matteson, MD, MPH, Consultant, Mayo Clinic; T. Bongartz, MD, MS, Vanderbilt University. crowson@mayo.edu.
Abstract
OBJECTIVE: To assess in-hospital gout flares in patients with gout. METHODS: Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. RESULTS: There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). CONCLUSION: Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.
OBJECTIVE: To assess in-hospital gout flares in patients with gout. METHODS: Hospitalizations were evaluated for gout flares in a cohort of Olmsted County, Minnesota, residents with incident gout in 1989-1992 or 2009-2010. RESULTS: There were 429 patients followed up to 5 years. Of these, 169 patients experienced 454 hospitalizations. Hospitalization rates increased without reaching statistical significance from 1989-1992 to 2009-2010 [rate ratio (RR) 1.19, 95% CI 0.98-1.45]. The gout flare rate increased significantly during hospitalization (RR 10.2, 95% CI 6.8-14.5). In-hospital gout flare increased the average hospital stay by 1.8 days (p < 0.001). CONCLUSION: Hospitalization increased the risk of gout flares 10-fold. In-hospital gout flares were associated with longer hospitalization.
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