| Literature DB >> 29959527 |
Ante Tonkic1,2, Jonatan Vukovic3,4, Pavle Vrebalov Cindro4, Valdi Pesutic Pisac3,5, Marija Tonkic3,6.
Abstract
Helicobacter pylori infections represent an important factor in the pathogenesis of chronic gastritis, peptic ulcer, MALT lymphoma and gastric adenocarcinoma. The recently published Maastricht V/Florence consensus report indicated that the urea breath test using 13 C urea still remains the best non-invasive test to diagnose H. pylori infections with high sensitivity and specificity. Among the stool antigen tests, the ELISA monoclonal antibody test is a rational option. Effective therapy should be based only on susceptibility testing in regions with documented high clarithromycin resistance (>15%). Advanced high-resolution endoscopic technologies enable increased diagnostic accuracy for detection of H. pylori infections.Entities:
Keywords: Diagnosis; Helicobacter pylori; Invasive test; Non-invasive test
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Year: 2018 PMID: 29959527 DOI: 10.1007/s00508-018-1356-6
Source DB: PubMed Journal: Wien Klin Wochenschr ISSN: 0043-5325 Impact factor: 1.704