Literature DB >> 29959172

Tuberculous arthritis: negative Xpert MTB/RIF assay does not rule out infection!

Rebecca Davis1, Clare Higgens1, Catherine Cosgrove1, Joshua Shur2, Paul Arkell2.   

Abstract

We present a case of a 31-year-old man of Indian origin with no previous medical history who presented with an inflamed knee. Treatment for bacterial infection was unsuccessful, and needle aspiration of the left knee effusion/collection was smear and culture positive for tuberculosis (TB), despite Xpert MTB/RIF being falsely negative. The patient was commenced on quadruple therapy for TB and within 2 months had improved significantly with no clinical evidence of ongoing inflammation. © Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  bone and joint infections; infections; infectious diseases; musculoskeletal and joint disorders; tb and other respiratory infections

Mesh：

Substances：

Year:  2018        PMID： 29959172      PMCID： PMC6040497          DOI： 10.1136/bcr-2018-224288

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  13 in total

1.  Diagnosis of extrapulmonary tuberculosis by smear, culture, and PCR using universal sample processing technology.

Authors:  Soumitesh Chakravorty; Manas Kamal Sen; Jaya Sivaswami Tyagi
Journal:  J Clin Microbiol       Date:  2005-09       Impact factor: 5.948

Review 2.  Extrapulmonary tuberculosis: an overview.

Authors:  Marjorie P Golden; Holenarasipur R Vikram
Journal:  Am Fam Physician       Date:  2005-11-01       Impact factor: 3.292

Review 3.  Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults.

Authors:  Karen R Steingart; Ian Schiller; David J Horne; Madhukar Pai; Catharina C Boehme; Nandini Dendukuri
Journal:  Cochrane Database Syst Rev       Date:  2014-01-21

Review 4.  Mycobacterial Musculoskeletal Infections.

Authors:  John I Hogan; Rocío M Hurtado; Sandra B Nelson
Journal:  Infect Dis Clin North Am       Date:  2017-03-11       Impact factor: 5.982

Review 5.  Laboratory Diagnosis of Extra-pulmonary Tuberculosis (EPTB) in Resource-constrained Setting: State of the Art, Challenges and the Need.

Authors:  Manju Purohit; Tehmina Mustafa
Journal:  J Clin Diagn Res       Date:  2015-04-01

Review 6.  Extrapulmonary tuberculosis.

Authors:  S K Sharma; A Mohan
Journal:  Indian J Med Res       Date:  2004-10       Impact factor: 2.375

7.  Improved diagnostic sensitivity for tuberculous meningitis with Xpert(®) MTB/RIF of centrifuged CSF.

Authors:  N C Bahr; L Tugume; R Rajasingham; R Kiggundu; D A Williams; B Morawski; D Alland; D B Meya; J Rhein; D R Boulware
Journal:  Int J Tuberc Lung Dis       Date:  2015-10       Impact factor: 2.373

Review 8.  Diagnostic accuracy of the Xpert MTB/RIF assay for extrapulmonary and pulmonary tuberculosis when testing non-respiratory samples: a systematic review.

Authors:  Laura Maynard-Smith; Natasha Larke; Jurgens A Peters; Stephen D Lawn
Journal:  BMC Infect Dis       Date:  2014-12-31       Impact factor: 3.090

9.  Tuberculous arthritis revisited as a forgotten cause of monoarticular arthritis.

Authors:  Mohammed J Al-Sayyad; Lutf A Abumunaser
Journal:  Ann Saudi Med       Date:  2011 Jul-Aug       Impact factor: 1.526

10.  Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study.

Authors:  Susan E Dorman; Samuel G Schumacher; David Alland; Pamela Nabeta; Derek T Armstrong; Bonnie King; Sandra L Hall; Soumitesh Chakravorty; Daniela M Cirillo; Nestani Tukvadze; Nino Bablishvili; Wendy Stevens; Lesley Scott; Camilla Rodrigues; Mubin I Kazi; Moses Joloba; Lydia Nakiyingi; Mark P Nicol; Yonas Ghebrekristos; Irene Anyango; Wilfred Murithi; Reynaldo Dietze; Renata Lyrio Peres; Alena Skrahina; Vera Auchynka; Kamal Kishore Chopra; Mahmud Hanif; Xin Liu; Xing Yuan; Catharina C Boehme; Jerrold J Ellner; Claudia M Denkinger
Journal:  Lancet Infect Dis       Date:  2017-11-30       Impact factor: 25.071
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