Literature DB >> 29958705

[Bilateral uveitis associated with nivolumab therapy].

A-L Rémond1, E Barreau2, P Le Hoang1, B Bodaghi1.   

Abstract

Immune-related adverse events (IRAEs) are rare but serious adverse events that may be associated with inhibitors of few immune control points. The purpose here is to report the case of an inflammatory ocular disease, potentially linked to the immunity and use of nivolumab, a new immunological agent used for the treatment of a solid tumor. In spite of the involvement of this treatment in the onset of inflammation, we must always seek another cause. It is possible to continue this treatment by considering the benefit/risk balance for each patient. Close collaboration between oncologists and ophthalmologists is necessary in the diagnosis and rapid management of these IRAE ocular related to these new emerging therapies.
Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Anti-PD1; Check point inhibitors; Chemotherapy; Chirurgie de la cataracte; Drug induced uveitis; Dysfonctionnement meibomien; Expressibilité meibomienne; Meibographie; Nivolumab; Posterior uveitis; Sécheresse oculaire; Uveitis

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Substances:

Year:  2018        PMID: 29958705     DOI: 10.1016/j.jfo.2017.10.009

Source DB:  PubMed          Journal:  J Fr Ophtalmol        ISSN: 0181-5512            Impact factor:   0.818


  3 in total

1.  Acute Bilateral Uveitis, Hypotony, and Cataracts Associated with Ipilimumab and Nivolumab Therapy: Optical Coherence Tomography Angiography Findings.

Authors:  Jessica C Lee; Ghadeer Al-Humimat; Karanjit S Kooner
Journal:  Case Rep Ophthalmol       Date:  2020-11-10

2.  Bilateral Panuveitis and Exudative Retinal Detachments Associated with Alpelisib.

Authors:  Yu Jeat Chong; Matthew Azzopardi; Mohammad Omar Tallouzi; David Spooner; Imran Masood; Yajati Ghosh; Sreekanth Sreekantam
Journal:  Case Rep Oncol       Date:  2022-08-03

3.  Ocular Inflammation Induced by Immune Checkpoint Inhibitors.

Authors:  Florence Chaudot; Pascal Sève; Antoine Rousseau; Alexandre Thibault Jacques Maria; Pierre Fournie; Pierre Lozach; Jeremy Keraen; Marion Servant; Romain Muller; Baptiste Gramont; Sara Touhami; Habeeb Mahmoud; Pierre-Antoine Quintart; Stéphane Dalle; Olivier Lambotte; Laurent Kodjikian; Yvan Jamilloux
Journal:  J Clin Med       Date:  2022-08-25       Impact factor: 4.964

  3 in total

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