Literature DB >> 29957217

Live imaging of cell division in 3D stem-cell organoid cultures.

Ana C F Bolhaqueiro1, Richard H van Jaarsveld1, Bas Ponsioen2, René M Overmeer3, Hugo J Snippert4, Geert J P L Kops5.   

Abstract

Examining cell behavior in its correct tissue context is a major challenge in cell biology. The recent development of mammalian stem cell-based organoid cultures offers exciting opportunities to visualize dynamic cellular events in a 3D tissue-like setting. We describe here an approach for live imaging of cell division processes in intestinal organoid cultures derived from human and mouse adult stem cells. These approaches can be extended to the analysis of cellular events in diseased tissue, such as patient-derived tumor organoids.
© 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Aneuploidy; Chromosome; Mitosis; Organoid; Stem cell; Tumor

Mesh：

Year:  2018        PMID： 29957217     DOI： 10.1016/bs.mcb.2018.03.016

Source DB:  PubMed          Journal:  Methods Cell Biol        ISSN： 0091-679X            Impact factor:   1.441


  7 in total

Review 1.  Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy.

Authors:  Arianna Fumagalli; Lotte Bruens; Colinda L G J Scheele; Jacco van Rheenen
Journal:  Cold Spring Harb Perspect Biol       Date:  2020-09-01       Impact factor: 9.708

Review 2.  Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders.

Authors:  Aurélie de Rus Jacquet; Hélèna L Denis; Francesca Cicchetti; Melanie Alpaugh
Journal:  Mol Psychiatry       Date:  2021-01-25       Impact factor: 13.437

3.  Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury.

Authors:  Tiane Chen; Maged Zeineldin; Blake A Johnson; Yi Dong; Akshay Narkar; Taibo Li; Jin Zhu; Rong Li; Tatianna C Larman
Journal:  Neoplasia       Date:  2021-04-24       Impact factor: 5.715

4.  On the role of p53 in the cellular response to aneuploidy.

Authors:  Akshay Narkar; Blake A Johnson; Pandurang Bharne; Jin Zhu; Veena Padmanaban; Debojyoti Biswas; Andrew Fraser; Pablo A Iglesias; Andrew J Ewald; Rong Li
Journal:  Cell Rep       Date:  2021-03-23       Impact factor: 9.423

5.  Fast in vitro protocol for the visualization and quantitative high-throughput analysis of sprouting angiogenesis by confocal microscopy.

Authors:  Lanette Kempers; Ivo van der Bijl; Anne-Marieke D van Stalborch; Bas Ponsioen; Coert Margadant
Journal:  STAR Protoc       Date:  2021-09-13

6.  Comparison of Cell and Organoid-Level Analysis of Patient-Derived 3D Organoids to Evaluate Tumor Cell Growth Dynamics and Drug Response.

Authors:  Seungil Kim; Sarah Choung; Ren X Sun; Nolan Ung; Natasha Hashemi; Emma J Fong; Roy Lau; Erin Spiller; Jordan Gasho; Jasmine Foo; Shannon M Mumenthaler
Journal:  SLAS Discov       Date:  2020-04-30       Impact factor: 3.341

Review 7.  Modeling the developmental origins of pediatric cancer to improve patient outcomes.

Authors:  James F Amatruda
Journal:  Dis Model Mech       Date:  2021-02-22       Impact factor: 5.732
  7 in total

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