Literature DB >> 29956627

Pharmacological Effects and Chemical Constituents of Bupleurum.

Peng Sun1,2, Yijie Li1, Sheng Wei1, Tingting Zhao1, Yang Wang3, Chunhong Song1, Ling Xue1,2, Fushun Wang4, Lingyun Xiao5, Jibiao Wu1, Mingqi Qiao1.   

Abstract

Radix Bupleuri has been used in traditional Chinese medicine for thousands of years, with confirmed curative effects. This plant is also used in healthy food and cosmetics. A recent increase in studies of Radix Bupleuri's chemical constituents (mainly comprising flavonoids, lignins, phenyl propanol derivatives, triterpenoid saponins, and volatile oils) and pharmacological effects motivates the aim of the present study: to review the chemical components and pharmacological effects of Radix Bupleuri. Our review found that Radix Bupleuri exhibits diverse pharmacological effects. More than 281 components have been isolated from Radix Bupleuri, including 15 flavonoids, 430 lignins, 12 phenyl propanol derivatives, 66 triterpenoid saponins, and 158 volatile oils. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Chinese medicine; Radix Bupleuri; chemical composition; flavonoids; pharmacological action; phenyl propanolzzm321990derivatives; triterpenoid saponins; volatile oils.

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Year:  2019        PMID： 29956627     DOI： 10.2174/1871520618666180628155931

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  6 in total

1.  Systematic Characterization and Identification of Saikosaponins in Extracts From Bupleurum marginatum var. stenophyllum Using UPLC-PDA-Q/TOF-MS.

Authors:  Wenxi Liu; Xianlong Cheng; Rong Kang; Yadan Wang; Xiaohan Guo; Wenguang Jing; Feng Wei; Shuangcheng Ma
Journal:  Front Chem       Date:  2021-09-30       Impact factor: 5.545

Review 2.  Traditional Chinese Medicines as Effective Reversals of Epithelial-Mesenchymal Transition Induced-Metastasis of Colorectal Cancer: Molecular Targets and Mechanisms.

Authors:  Hongzhang Ge; Chao Xu; Haitao Chen; Ling Liu; Lei Zhang; Changhong Wu; Yi Lu; Qinghua Yao
Journal:  Front Pharmacol       Date:  2022-03-04       Impact factor: 5.810

3.  Metabolomics Analysis Reveals the Differences Between Bupleurum chinense DC. and Bupleurum scorzonerifolium Willd.

Authors:  Xuejie Qu; Shanqun Hu; Tong Li; Jiaqi Zhang; Baoshun Wang; Changli Liu
Journal:  Front Plant Sci       Date:  2022-07-13       Impact factor: 6.627

4.  Quantitative Analysis and Differential Evaluation of Radix Bupleuri Cultivated in Different Regions Based on HPLC-MS and GC-MS Combined with Multivariate Statistical Analysis.

Authors:  Zhenhuan Wang; Huanxi Zhao; Lu Tian; Mengya Zhao; Yusheng Xiao; Shuying Liu; Yang Xiu
Journal:  Molecules       Date:  2022-07-28       Impact factor: 4.927

5.  Assembly and comparative analysis of the complete mitochondrial genome of Bupleurum chinense DC.

Authors:  Yonggang Qiao; Xinrui Zhang; Zheng Li; Yun Song; Zhe Sun
Journal:  BMC Genomics       Date:  2022-09-21       Impact factor: 4.547

6.  Comprehensive comparison on the anti-inflammation and GC-MS-based metabolomics discrimination between Bupleuri chinense DC. and B. scorzonerifolium Willd.

Authors:  Mingming Zhao; Linxuan Xiao; Ke-Gang Linghu; Guanding Zhao; Qiling Chen; Liyu Shen; Parsa Dar; Meiwan Chen; Yuan Hu; Jinming Zhang; Hua Yu
Journal:  Front Pharmacol       Date:  2022-09-14       Impact factor: 5.988
  6 in total

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