| Literature DB >> 29956139 |
J Morgan Knight1, Evan Li1, Hui-Ying Tung2, Cameron Landers1, Jake Wheeler1, Farrah Kheradmand1,2,3,4, David B Corry5,6,7,8.
Abstract
Allergic airway diseases (asthma and chronic rhinosinusitis) are among the most common of all human diseases in heavily industrialized societies. Animal models of asthma have provided remarkable insight into allergic disease pathogenesis and will continue to drive the discovery of new therapeutic insights. We provide in this chapter a detailed protocol for inducing allergic immunity in the lungs of mice using a purified fungal protease and include related protocols for assessing immune endpoints.Entities:
Keywords: Airway hyperresponsiveness; Allergic immunity; Asthma; Fungi; Protease; TH2 cell
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Year: 2018 PMID： 29956139 DOI： 10.1007/978-1-4939-7896-0_1
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745