Literature DB >> 2995499

Leukotriene B4 and 12-hydroxyeicosatetraenoic acid stimulate epidermal proliferation in vivo in the guinea pig.

C C Chan, L Duhamel, A Ford-Hutchison.   

Abstract

Epidermal proliferation was studied in the guinea-pig ear in vivo using the incorporation of [3H]thymidine into DNA as a measure of cell proliferation. Twenty-four-hour pretreatment of the skin topically with nanomolar amounts of either leukotriene B4 (LTB4), 12-hydroxyeicosatetraenoic acid, ionophore A23187, or the epidermal mitogen 12-O-tetradecanoylphorbol-13-acetate induced dose-dependent increases in epidermal proliferation. The stimulatory effect of LTB4 was stereospecific since a number of biologically inactive LTB4 stereoisomers had no effect.

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Year:  1985        PMID： 2995499     DOI： 10.1111/1523-1747.ep12276933

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  21 in total

1.  Heterogeneous distribution of lipoxygenase products in psoriatic skin lesions.

Authors:  K Fogh; J Kiil; T Herlin; T Ternowitz; K Kragballe
Journal:  Arch Dermatol Res       Date:  1987       Impact factor: 3.017

Review 2.  Metabolic interactions between eicosanoids in blood and vascular cells.

Authors:  M Lagarde; N Gualde; M Rigaud
Journal:  Biochem J       Date:  1989-01-15       Impact factor: 3.857

3.  Alterations in Epidermal Eicosanoid Metabolism Contribute to Inflammation and Impaired Late Differentiation in FLG-Mutated Atopic Dermatitis.

Authors:  Stefan Blunder; Ralph Rühl; Verena Moosbrugger-Martinz; Christine Krimmel; Anita Geisler; Huiting Zhu; Debra Crumrine; Peter M Elias; Robert Gruber; Matthias Schmuth; Sandrine Dubrac
Journal:  J Invest Dermatol       Date:  2016-10-26       Impact factor: 8.551

4.  Guinea pig epidermis generates putative anti-inflammatory metabolites from fish oil polyunsaturated fatty acids.

Authors:  C Miller; R Y Yamaguchi; V A Ziboh
Journal:  Lipids       Date:  1989-12       Impact factor: 1.880

5.  Influence of phospholipid liposomes (PLL) on UVB-induced erythema formation.

Authors:  B Thiele; M Ghyczy; C Lunow; H M Teichert; H H Wolff
Journal:  Arch Dermatol Res       Date:  1993       Impact factor: 3.017

6.  Monohydroxy fatty acids esterified to phospholipids are decreased in lesional psoriatic skin.

Authors:  B Grøn; L Iversen; V Ziboh; K Kragballe
Journal:  Arch Dermatol Res       Date:  1993       Impact factor: 3.017

Review 7.  Modulation of mitogenesis by liver fatty acid binding protein.

Authors:  S Sorof
Journal:  Cancer Metastasis Rev       Date:  1994-12       Impact factor: 9.264

Review 8.  12-lipoxygenases and 12(S)-HETE: role in cancer metastasis.

Authors:  K V Honn; D G Tang; X Gao; I A Butovich; B Liu; J Timar; W Hagmann
Journal:  Cancer Metastasis Rev       Date:  1994-12       Impact factor: 9.264

9.  Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2.

Authors:  A Miyake; H Yamamoto; E Kubota; K Hamaguchi; A Kouda; K Honda; H Kawashima
Journal:  Br J Pharmacol       Date:  1993-09       Impact factor: 8.739

10.  Dithranol-induced down-regulation of 12(S)-hydroxyeicosatetraenoic acid [12(S)-HETE] receptors in a human epidermal cell line.

Authors:  L Kemény; E Gross; P Arenberger; T Ruzicka
Journal:  Arch Dermatol Res       Date:  1991       Impact factor: 3.017
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