Literature DB >> 29954750

Improved CNS exposure to tocilizumab after cerebrospinal fluid compared to intravenous administration in rhesus macaques.

Anandani Nellan1,2, Cynthia M Lester McCully3, Rafael Cruz Garcia3, Nalini Jayaprakash3, Brigitte C Widemann3, Daniel W Lee4, Katherine E Warren3.   

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Year:  2018        PMID： 29954750      PMCID： PMC6086204          DOI： 10.1182/blood-2018-05-846428

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


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  18 in total

1.  T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial.

Authors:  Daniel W Lee; James N Kochenderfer; Maryalice Stetler-Stevenson; Yongzhi K Cui; Cindy Delbrook; Steven A Feldman; Terry J Fry; Rimas Orentas; Marianna Sabatino; Nirali N Shah; Seth M Steinberg; Dave Stroncek; Nick Tschernia; Constance Yuan; Hua Zhang; Ling Zhang; Steven A Rosenberg; Alan S Wayne; Crystal L Mackall
Journal:  Lancet       Date:  2014-10-13       Impact factor: 79.321

2.  Chimeric antigen receptor T cells for sustained remissions in leukemia.

Authors:  Shannon L Maude; Noelle Frey; Pamela A Shaw; Richard Aplenc; David M Barrett; Nancy J Bunin; Anne Chew; Vanessa E Gonzalez; Zhaohui Zheng; Simon F Lacey; Yolanda D Mahnke; Jan J Melenhorst; Susan R Rheingold; Angela Shen; David T Teachey; Bruce L Levine; Carl H June; David L Porter; Stephan A Grupp
Journal:  N Engl J Med       Date:  2014-10-16       Impact factor: 91.245

3.  Interleukin 6-Mediated Endothelial Barrier Disturbances Can Be Attenuated by Blockade of the IL6 Receptor Expressed in Brain Microvascular Endothelial Cells.

Authors:  Kinga G Blecharz-Lang; Josephin Wagner; Alexa Fries; Melina Nieminen-Kelhä; Jörg Rösner; Ulf C Schneider; Peter Vajkoczy
Journal:  Transl Stroke Res       Date:  2018-02-10       Impact factor: 6.829

4.  Endothelial Activation and Blood-Brain Barrier Disruption in Neurotoxicity after Adoptive Immunotherapy with CD19 CAR-T Cells.

Authors:  Juliane Gust; Kevin A Hay; Laïla-Aïcha Hanafi; Daniel Li; David Myerson; Luis F Gonzalez-Cuyar; Cecilia Yeung; W Conrad Liles; Mark Wurfel; Jose A Lopez; Junmei Chen; Dominic Chung; Susanna Harju-Baker; Tahsin Özpolat; Kathleen R Fink; Stanley R Riddell; David G Maloney; Cameron J Turtle
Journal:  Cancer Discov       Date:  2017-10-12       Impact factor: 39.397

5.  CNS Endothelial Cell Activation Emerges as a Driver of CAR T Cell-Associated Neurotoxicity.

Authors:  Crystal L Mackall; David B Miklos
Journal:  Cancer Discov       Date:  2017-12       Impact factor: 39.397

6.  Chimeric Antigen Receptor T Cell-Mediated Neurotoxicity in Nonhuman Primates.

Authors:  Agne Taraseviciute; Victor Tkachev; Rafael Ponce; Cameron J Turtle; Jessica M Snyder; H Denny Liggitt; David Myerson; Luis Gonzalez-Cuyar; Audrey Baldessari; Chris English; Alison Yu; Hengqi Zheng; Scott N Furlan; Daniel J Hunt; Virginia Hoglund; Olivia Finney; Hannah Brakke; Bruce R Blazar; Carolina Berger; Stanley R Riddell; Rebecca Gardner; Leslie S Kean; Michael C Jensen
Journal:  Cancer Discov       Date:  2018-03-21       Impact factor: 39.397

7.  Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia.

Authors:  Marco L Davila; Isabelle Riviere; Xiuyan Wang; Shirley Bartido; Jae Park; Kevin Curran; Stephen S Chung; Jolanta Stefanski; Oriana Borquez-Ojeda; Malgorzata Olszewska; Jinrong Qu; Teresa Wasielewska; Qing He; Mitsu Fink; Himaly Shinglot; Maher Youssif; Mark Satter; Yongzeng Wang; James Hosey; Hilda Quintanilla; Elizabeth Halton; Yvette Bernal; Diana C G Bouhassira; Maria E Arcila; Mithat Gonen; Gail J Roboz; Peter Maslak; Dan Douer; Mark G Frattini; Sergio Giralt; Michel Sadelain; Renier Brentjens
Journal:  Sci Transl Med       Date:  2014-02-19       Impact factor: 17.956

8.  Current concepts in the diagnosis and management of cytokine release syndrome.

Authors:  Daniel W Lee; Rebecca Gardner; David L Porter; Chrystal U Louis; Nabil Ahmed; Michael Jensen; Stephan A Grupp; Crystal L Mackall
Journal:  Blood       Date:  2014-05-29       Impact factor: 22.113

9.  Serum tocilizumab trough concentration can be used to monitor systemic IL-6 receptor blockade in patients with rheumatoid arthritis: a prospective observational cohort study.

Authors:  E L Kneepkens; Iam van den Oever; C H Plasencia; D Pascual-Salcedo; A de Vries; M Hart; M T Nurmohamed; A Balsa; T Rispens; G Wolbink
Journal:  Scand J Rheumatol       Date:  2016-07-20       Impact factor: 3.641

Review 10.  Tocilizumab in the treatment of rheumatoid arthritis and beyond.

Authors:  Anjali Shetty; Rebekah Hanson; Peter Korsten; Munir Shawagfeh; Shiva Arami; Suncica Volkov; Olga Vila; William Swedler; Abdel Naser Shunaigat; Sameer Smadi; Ray Sawaqed; David Perkins; Shiva Shahrara; Nadera J Sweiss
Journal:  Drug Des Devel Ther       Date:  2014-03-28       Impact factor: 4.162
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  26 in total

Review 1.  Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

Authors:  Talha Badar; Nirav N Shah
Journal:  Curr Treat Options Oncol       Date:  2020-02-05

2.  Chimeric antigen receptor-T cells with cytokine neutralizing capacity.

Authors:  Adrian H J Tan; Natasha Vinanica; Dario Campana
Journal:  Blood Adv       Date:  2020-04-14

Review 3.  Recent advances in CAR T-cell toxicity: Mechanisms, manifestations and management.

Authors:  Jennifer N Brudno; James N Kochenderfer
Journal:  Blood Rev       Date:  2018-11-14       Impact factor: 8.250

4.  Origin and Function of Stress-Induced IL-6 in Murine Models.

Authors:  Hua Qing; Reina Desrouleaux; Kavita Israni-Winger; Yann S Mineur; Nia Fogelman; Cuiling Zhang; Saleh Rashed; Noah W Palm; Rajita Sinha; Marina R Picciotto; Rachel J Perry; Andrew Wang
Journal:  Cell       Date:  2020-06-30       Impact factor: 41.582

Review 5.  Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review.

Authors:  Adeel S Zubair; Lindsay S McAlpine; Tova Gardin; Shelli Farhadian; Deena E Kuruvilla; Serena Spudich
Journal:  JAMA Neurol       Date:  2020-08-01       Impact factor: 18.302

Review 6.  Assessment and management of cytokine release syndrome and neurotoxicity following CD19 CAR-T cell therapy.

Authors:  Cassie K Chou; Cameron J Turtle
Journal:  Expert Opin Biol Ther       Date:  2020-02-24       Impact factor: 4.388

7.  Flow Rate and Apparent Volume of Cerebrospinal Fluid in Rhesus Macaques (Macaca mulatta) Based on the Pharmacokinetics of Intrathecally Administered Inulin.

Authors:  Cynthia M Lester McCully; Louis T Rodgers; Rafael Cruz Garica; Marvin L Thomas; Cody J Peer; William D Figg; Dennis E Barnard; Katherine E Warren
Journal:  Comp Med       Date:  2020-10-12       Impact factor: 0.982

Review 8.  Taming the beast: CRS and ICANS after CAR T-cell therapy for ALL.

Authors:  Vipul S Sheth; Jordan Gauthier
Journal:  Bone Marrow Transplant       Date:  2020-11-24       Impact factor: 5.483

9.  Treatment Effects of Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response After Out-of-Hospital Cardiac Arrest (The IMICA Trial): A Double-Blinded, Placebo-Controlled, Single-Center, Randomized, Clinical Trial.

Authors:  Martin Abild Stengaard Meyer; Sebastian Wiberg; Johannes Grand; Anna Sina Pettersson Meyer; Laust Emil Roelsgaard Obling; Martin Frydland; Jakob Hartvig Thomsen; Jakob Josiassen; Jacob Eifer Møller; Jesper Kjaergaard; Christian Hassager
Journal:  Circulation       Date:  2021-03-22       Impact factor: 29.690

Review 10.  CAR-T Cell Therapy: Mechanism, Management, and Mitigation of Inflammatory Toxicities.

Authors:  Joseph W Fischer; Nirjal Bhattarai
Journal:  Front Immunol       Date:  2021-06-18       Impact factor: 7.561
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