Heitham Awadalla1, Sufian K Noor2, Wadie M Elmadhoun3, Sarra O Bushara2, Ahmed O Almobarak4, Amel Abdalrhim Sulaiman5, Mohamed H Ahmed6. 1. Department of community Medicine, Faculty of Medicine, University of Khartoum, Sudan. 2. Department of Medicine, Nile Valley University, Atbara, Sudan. 3. Department of Pathology, Nile Valley University, Atbara, Sudan. 4. Department of Pathology, Faculty of Medicine, University of Medical Sciences and Technology, Khartoum, Sudan. 5. Research & Information Unit, Public Health Administration - MOH, Qassim Region, Saudi Arabia. 6. Department of Medicine and HIV metabolic clinic, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes, Buckinghamshire, UK. Electronic address: Mohamed.Hassan-Ahmed@mkuh.nhs.uk.
Abstract
BACKGROUND: Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. Dyslipidemia is a major complication of diabetes and an important risk factor for cardiovascular disease (CVD). The objective of this study was to determine the prevalence of dyslipidemia and its co-relation with the glycemic control in individuals with diabetes in River Nile State, Sudan. METHODS: Individuals with diabetes attended, Naserudin Karamalla Diabetic (NKDM) Centre, in Atbara teaching hospital during study period, who volunteered to participate were included. Only those on treatment for DM for at least one year were included. Venous samples were collected for cholesterol, triglycerides, HDL, LDL, blood glucose and Glycosylated hemoglobin. Participants were interviewed using standardized pretested questionnaire to record medical history and sociodemographic characteristics. Blood pressure, body mass index (BMI) and waist circumference were measured. RESULTS: A total of 188 individuals were included. The mean age was 49.5 + 13.9 and (128) 68.1% were females. Most patients were having DM for at least 3-5 years 69 (36.7%). Poor diabetes control (HbA1c >7) was recorded in 87.2%, hypercholesterolemia, hypertriglyceridemia and high LDL were identified in 36.6%, 27.7% and 26.6% respectively. In addition, HDL was low in 61.2% of patients. CONCLUSION: Low HDL is a prominent feature in two thirds of individuals with diabetes, while high cholesterol and high triglyceride were seen in over one quarter.
BACKGROUND:Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. Dyslipidemia is a major complication of diabetes and an important risk factor for cardiovascular disease (CVD). The objective of this study was to determine the prevalence of dyslipidemia and its co-relation with the glycemic control in individuals with diabetes in River Nile State, Sudan. METHODS: Individuals with diabetes attended, Naserudin Karamalla Diabetic (NKDM) Centre, in Atbara teaching hospital during study period, who volunteered to participate were included. Only those on treatment for DM for at least one year were included. Venous samples were collected for cholesterol, triglycerides, HDL, LDL, blood glucose and Glycosylated hemoglobin. Participants were interviewed using standardized pretested questionnaire to record medical history and sociodemographic characteristics. Blood pressure, body mass index (BMI) and waist circumference were measured. RESULTS: A total of 188 individuals were included. The mean age was 49.5 + 13.9 and (128) 68.1% were females. Most patients were having DM for at least 3-5 years 69 (36.7%). Poor diabetes control (HbA1c >7) was recorded in 87.2%, hypercholesterolemia, hypertriglyceridemia and high LDL were identified in 36.6%, 27.7% and 26.6% respectively. In addition, HDL was low in 61.2% of patients. CONCLUSION: Low HDL is a prominent feature in two thirds of individuals with diabetes, while high cholesterol and high triglyceride were seen in over one quarter.
Authors: Hussain A Al Ghadeer; Mohammed Al Barqi; Abdullah Almaqhawi; Amal S Alsultan; Jinan A Alghafli; Murtada A AlOmaish; Zuhur A AlGhanem; Amer H Alsaqar; Abrar T Alatiyyah; Yasamiyan A Alburayh; Abdulatif AlOmair; Afaf I Almuhaysin; Ali A Alsaeed Journal: Cureus Date: 2021-12-06