Literature DB >> 2995445

Deoxyribonucleic acid polymorphism in the apolipoprotein A-1-C-III gene cluster. Association with hypertriglyceridemia.

A Rees, J Stocks, C R Sharpe, M A Vella, C C Shoulders, J Katz, N I Jowett, F E Baralle, D J Galton.   

Abstract

A DNA sequence polymorphism, revealed by digestion of human DNA with the restriction endonuclease Sst-1 and hybridization with an apolipoprotein A-I complementary DNA clone, has been shown to be located in or close to the 3' noncoding region of the apolipoprotein C-III gene. This polymorphism is found in significantly increased prevalence (P less than 0.001) in Caucasian hypertriglyceridemic subjects compared with race-matched controls, and its distribution in normal individuals of differing racial origins is reported. Furthermore, no alteration of high density lipoprotein or apolipoprotein A-I and apolipoprotein C-III phenotypes was observed in individuals with or without the polymorphism.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 2995445      PMCID： PMC423995          DOI： 10.1172/JCI112062

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  18 in total

1.  Analysis of rat serum apolipoproteins by isoelectric focusing. II. Studies on the low molecular weight subunits.

Authors:  J B Swaney; L I Gidez
Journal:  J Lipid Res       Date:  1977-01       Impact factor: 5.922

2.  Genetic study of hyperlipoproteinaemia types IV and V.

Authors:  J François; F Lentini; P Hoste; R Rottiers
Journal:  Clin Genet       Date:  1977-10       Impact factor: 4.438

3.  Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

Authors:  L M Kunkel; K D Smith; S H Boyer; D S Borgaonkar; S S Wachtel; O J Miller; W R Breg; H W Jones; J M Rary
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

4.  An abnormal triglyceride-rich lipoprotein carrying excess apolipoprotein C-II.

Authors:  J Stocks; G Holdsworth; P Dodson; D J Galton
Journal:  Atherosclerosis       Date:  1981 Jan-Feb       Impact factor: 5.162

5.  Human very low density lipoprotein apolipoprotein E isoprotein polymorphism is explained by genetic variation and posttranslational modification.

Authors:  V I Zannis; J L Breslow
Journal:  Biochemistry       Date:  1981-02-17       Impact factor: 3.162

6.  Regulation of the hepatic uptake of triglyceride-rich lipoproteins in the rat. Opposing effects of homologous apolipoprotein E and individual C apoproteins.

Authors:  E Windler; Y Chao; R J Havel
Journal:  J Biol Chem       Date:  1980-09-10       Impact factor: 5.157

7.  A-IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family.

Authors:  G Franceschini; C R Sirtori; A Capurso; K H Weisgraber; R W Mahley
Journal:  J Clin Invest       Date:  1980-11       Impact factor: 14.808

8.  An abnormal triglyceride-rich lipoprotein containing excess sialylated apolipoprotein C-III.

Authors:  G Holdsworth; J Stocks; P Dodson; D J Galton
Journal:  J Clin Invest       Date:  1982-04       Impact factor: 14.808

9.  Hypertriglyceridemia associated with deficiency of apolipoprotein C-II.

Authors:  W C Breckenridge; J A Little; G Steiner; A Chow; M Poapst
Journal:  N Engl J Med       Date:  1978-06-08       Impact factor: 91.245

10.  Fish eye disease: a new familial condition with massive corneal opacities and dyslipoproteinaemia.

Authors:  L A Carlson
Journal:  Eur J Clin Invest       Date:  1982-02       Impact factor: 4.686
View more
  39 in total

1.  A multilocus genotyping assay for candidate markers of cardiovascular disease risk.

Authors:  S Cheng; M A Grow; C Pallaud; W Klitz; H A Erlich; S Visvikis; J J Chen; C R Pullinger; M J Malloy; G Siest; J P Kane
Journal:  Genome Res       Date:  1999-10       Impact factor: 9.043

2.  Extended haplotypes and linkage disequilibrium between 11 markers at the APOA1-C3-A4 gene cluster on chromosome 11.

Authors:  P Benlian; C Boileau; N Loux; D Pastier; J Masliah; M Coulon; M Nigou; A Ragab; J Guimard; J B Ruidavets
Journal:  Am J Hum Genet       Date:  1991-05       Impact factor: 11.025

3.  Estimation of Hardy-Weinberg and pairwise disequilibrium in the apolipoprotein AI-CIII-AIV gene cluster.

Authors:  M B Haviland; A M Kessling; J Davignon; C F Sing
Journal:  Am J Hum Genet       Date:  1991-08       Impact factor: 11.025

4.  Multiple restriction fragment length polymorphisms at the insulin receptor locus: a highly informative marker for linkage analysis.

Authors:  S C Elbein; L Corsetti; A Ullrich; M A Permutt
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

5.  Study of apolipoproteinc3 Sstl polymorphism in healthy volunteers from Northern India.

Authors:  S Chhabra; D P Agarwal; S Vasisht; K Luthra; R Narang; S C Manchanda; L M Srivastava; N Das
Journal:  Indian J Clin Biochem       Date:  2003-07

6.  The genetic aspects of atherosclerosis and hyperlipidemia.

Authors:  M R Hayden
Journal:  CMAJ       Date:  1989-07-15       Impact factor: 8.262

7.  Haplotypes identified by DNA polymorphisms at the apolipoprotein A-1 and C-III loci and hypertriglyceridaemia. A study in a Japanese population.

Authors:  A Rees; J Stocks; H Paul; Y Ohuchi; D Galton
Journal:  Hum Genet       Date:  1986-02       Impact factor: 4.132

8.  Apo CIII gene transcription is regulated by a cytokine inducible NF-kappa B element.

Authors:  P J Gruber; A Torres-Rosado; M L Wolak; T Leff
Journal:  Nucleic Acids Res       Date:  1994-06-25       Impact factor: 16.971

9.  An apolipoprotein CIII marker associated with hypertriglyceridemia in Caucasians also confers increased risk in a west Japanese population.

Authors:  Q Zeng; M Dammerman; Y Takada; A Matsunaga; J L Breslow; J Sasaki
Journal:  Hum Genet       Date:  1995-04       Impact factor: 4.132

10.  Linkage disequilibrium of three polymorphic RFLP markers in the apolipoprotein AI-CIII gene cluster on chromosome 11.

Authors:  O Marasco; F Melina; E Mele; B Quaresima; A Zingone; E Focarelli; E Picciotti; M L Martelli; L Fotino; M F Vigna
Journal:  Hum Genet       Date:  1993-03       Impact factor: 4.132
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.