Literature DB >> 29953221

Toxicological Assessment of Mineral Hydrocarbons in Foods: State of Present Discussions.

Koni Grob1.   

Abstract

The evaluation of mineral oils by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) provided high acceptable daily intakes for classes largely falling into the mass range strongly accumulated by humans. Because they are roughly 2 orders of magnitude above the present exposure, they authorize strongly increased exposure. An approach based on accumulation seems more adequate. Increased organ weights might be more critical than granulomas. Aromatic hydrocarbons with 1-2 aromatic rings should be distinguished from those with at least 3 aromatic rings. If mineral oil saturated hydrocarbon limits were low, no limit might be needed for the 1-2 ring aromatics. It should be considered to phase out substantial use of mineral oils in food application.

Entities:  

Keywords:  granuloma formation; increased organ weight; mineral oil aromatic hydrocarbons (MOAH); mineral oil saturated hydrocarbons (MOSH)

Mesh:

Substances:

Year:  2018        PMID: 29953221     DOI: 10.1021/acs.jafc.8b02225

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN: 0021-8561            Impact factor:   5.279


  1 in total

1.  Transformer mineral oil ingestion induces systemic sub-acute toxicity in Wistar rats.

Authors:  Grace N Otunga; Geoffrey K Maiyoh; Benson N Macharia; Vivian C Tuei
Journal:  Heliyon       Date:  2019-12-08
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.