Literature DB >> 29951467

MODIC CHANGES IN ADULTS WITH CHRONIC LOW BACK PAIN IN NORTH CENTRAL NIGERIA.

O I Oyinloye1, J O Bamidele1, G O Popoola2.   

Abstract

BACKGROUND: Modic changes in the endplates of the vertebral bodies have been associated with low back pain. There is however paucity of information on the pattern of Modic changes in the lumbosacral spine in Nigerians with low back pain. AIM: To determine the prevalence of Modic changes in patients with chronic low back pain in our environment. DESIGN OF STUDY: Cross-sectional longitudinal study. SETTINGS: University of Ilorin Teaching Hospital, Ilorin, Nigeria.
METHODOLOGY: A total of 147 consecutive adults who had MRI of the lumbosacral spine for chronic low back pain were examined for the presence of Modic changes.
RESULTS: 35(23.8%) individuals had Modic changes present out of I47 patients with low back pain evaluated.Out of the 735 lumbar vertebral endplates evaluated, 90(12.2%) had Modic changes present. Among the endplates with Modic changes, 36(40%) were type I, been the most common in our sample, while 27(30%) were type II and type III each.
CONCLUSION: This study has shown that Modic changes occurred more frequently at the end plates of lower lumbar vertebrae(L4/L5, and L5/S1) and Type I was the most common while Type II and III had equal prevalence; the changes occurred more frequently with increasing age suggesting these changes are degenerative in nature.

Entities:  

Keywords:  Low back pain; MRI; Modic changes; Nigeria

Year:  2017        PMID: 29951467      PMCID: PMC6016746     

Source DB:  PubMed          Journal:  J West Afr Coll Surg        ISSN: 2276-6944


  24 in total

1.  Modic changes following lumbar disc herniation.

Authors:  Hanne B Albert; Claus Manniche
Journal:  Eur Spine J       Date:  2007-03-03       Impact factor: 3.134

Review 2.  Vertebral endplate signal changes (Modic change): a systematic literature review of prevalence and association with non-specific low back pain.

Authors:  Tue Secher Jensen; Jaro Karppinen; Joan S Sorensen; Jaakko Niinimäki; Charlotte Leboeuf-Yde
Journal:  Eur Spine J       Date:  2008-09-12       Impact factor: 3.134

Review 3.  Modic changes: a systematic review of the literature.

Authors:  Yue-Hui Zhang; Chang-Qing Zhao; Lei-Sheng Jiang; Xiao-Dong Chen; Li-Yang Dai
Journal:  Eur Spine J       Date:  2008-08-27       Impact factor: 3.134

4.  Predictors of new vertebral endplate signal (Modic) changes in the general population.

Authors:  Tue Secher Jensen; Per Kjaer; Lars Korsholm; Tom Bendix; Joan S Sorensen; Claus Manniche; Charlotte Leboeuf-Yde
Journal:  Eur Spine J       Date:  2009-11-18       Impact factor: 3.134

5.  Modic changes and their associations with clinical findings.

Authors:  Per Kjaer; Lars Korsholm; Tom Bendix; Joan S Sorensen; Charlotte Leboeuf-Yde
Journal:  Eur Spine J       Date:  2006-08-09       Impact factor: 3.134

6.  Tumor necrosis factor-immunoreactive cells and PGP 9.5-immunoreactive nerve fibers in vertebral endplates of patients with discogenic low back Pain and Modic Type 1 or Type 2 changes on MRI.

Authors:  Seiji Ohtori; Gen Inoue; Toshinori Ito; Takana Koshi; Tomoyuki Ozawa; Hideo Doya; Tomoko Saito; Hideshige Moriya; Kazuhisa Takahashi
Journal:  Spine (Phila Pa 1976)       Date:  2006-04-20       Impact factor: 3.468

7.  The Longitudinal Assessment of Imaging and Disability of the Back (LAIDBack) Study: baseline data.

Authors:  J J Jarvik; W Hollingworth; P Heagerty; D R Haynor; R A Deyo
Journal:  Spine (Phila Pa 1976)       Date:  2001-05-15       Impact factor: 3.468

8.  The location of Modic changes in the lumbar spine: a meta-analysis.

Authors:  Zhe-Yu Huang; Hai-Chao Xu; Tao Lei; Qing-Long Li; Ai-Min Wu; Wen-Fei Ni
Journal:  Eur Spine J       Date:  2016-02-25       Impact factor: 3.134

9.  Is the development of Modic changes associated with clinical symptoms? A 14-month cohort study with MRI.

Authors:  Rikke K Jensen; Charlotte Leboeuf-Yde; Niels Wedderkopp; Joan S Sorensen; Tue S Jensen; Claus Manniche
Journal:  Eur Spine J       Date:  2012-04-24       Impact factor: 3.134

10.  MR imaging of marrow changes adjacent to end plates in degenerative lumbar disk disease.

Authors:  A de Roos; H Kressel; C Spritzer; M Dalinka
Journal:  AJR Am J Roentgenol       Date:  1987-09       Impact factor: 3.959

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  1 in total

1.  Serum Biomarkers for Connective Tissue and Basement Membrane Remodeling are Associated with Vertebral Endplate Bone Marrow Lesions as Seen on MRI (Modic Changes).

Authors:  Stefan Dudli; Alexander Ballatori; Anne-Christine Bay-Jensen; Zachary L McCormick; Conor W O'Neill; Sibel Demir-Deviren; Roland Krug; Irina Heggli; Astrid Juengel; Jaro Karppinen; Florian Brunner; Mazda Farshad; Oliver Distler; Jeffrey C Lotz; Aaron J Fields
Journal:  Int J Mol Sci       Date:  2020-05-27       Impact factor: 6.208

  1 in total

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