Literature DB >> 2995112

Autophagy and lysosomal proteolysis in the liver.

B Grinde.   

Abstract

Autophagy is defined as any process whereby cellular macromolecules destined for degradation gain access to the lysosomes. A review is presented on the physiological significance, mechanisms and regulation of autophagy in hepatocytes, concentrating on the issue of regulation. The article ends by discussing techniques available for future research.

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Year:  1985        PMID： 2995112     DOI： 10.1007/bf01951685

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  75 in total

1.  Concerning a possible mechanism for selective capture of cytoplasmic proteins by lysosomes.

Authors:  R T Dean
Journal:  Biochem Biophys Res Commun       Date:  1975-11-17       Impact factor: 3.575

2.  Effect of carboxylic ionophores on lysosomal protein degradation in rat hepatocytes.

Authors:  B Grinde
Journal:  Exp Cell Res       Date:  1983-11       Impact factor: 3.905

3.  Inhibitors of lysosomal function.

Authors:  P O Seglen
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

4.  Injection of proteins into primary rat hepatocytes by erythrocyte-mediated techniques.

Authors:  P A Docherty; N N Aronson
Journal:  Biochem Biophys Res Commun       Date:  1982-11-30       Impact factor: 3.575

5.  Degradation of proteins in rat liver mitochondrial outer membrane transplanted into different cell types. Evidence for alternative processing.

Authors:  S M Russell; J S Amenta; R J Mayer
Journal:  Biochem J       Date:  1984-06-01       Impact factor: 3.857

6.  Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields.

Authors:  D E Knight; P F Baker
Journal:  J Membr Biol       Date:  1982       Impact factor: 1.843

7.  Degradation of microinjected methylated and unmethylated proteins in hepatoma tissue culture cells.

Authors:  R Katznelson; R G Kulka
Journal:  J Biol Chem       Date:  1983-08-25       Impact factor: 5.157

Review 8.  Mechanisms of protein turnover in cultured cells.

Authors:  J S Amenta; S C Brocher
Journal:  Life Sci       Date:  1981-03-16       Impact factor: 5.037

9.  Quantitative correlation between proteolysis and macro- and microautophagy in mouse hepatocytes during starvation and refeeding.

Authors:  G E Mortimore; N J Hutson; C A Surmacz
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

10.  The synthesis and turnover of rat liver peroxisomes. II. Turnover of peroxisome proteins.

Authors:  B Poole; F Leighton; C De Duve
Journal:  J Cell Biol       Date:  1969-05       Impact factor: 10.539
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  4 in total

1.  Synthesis and screening of 3-MA derivatives for autophagy inhibitors.

Authors:  Yanyang Wu; Xin Wang; Haijing Guo; Bo Zhang; Xiao-Bo Zhang; Zhang-Jie Shi; Li Yu
Journal:  Autophagy       Date:  2013-02-14       Impact factor: 16.016

2.  Protein kinase-dependent effects of okadaic acid on hepatocytic autophagy and cytoskeletal integrity.

Authors:  I Holen; P B Gordon; P O Seglen
Journal:  Biochem J       Date:  1992-06-15       Impact factor: 3.857

3.  Vanadate inhibits degradation of short-lived, but not of long-lived, proteins in L-132 human cells.

Authors:  J L Vargas; F Aniento; J Cervera; E Knecht
Journal:  Biochem J       Date:  1989-02-15       Impact factor: 3.857

4.  Ultrastructural and biochemical characterization of autophagy in higher plant cells subjected to carbon deprivation: control by the supply of mitochondria with respiratory substrates.

Authors:  S Aubert; E Gout; R Bligny; D Marty-Mazars; F Barrieu; J Alabouvette; F Marty; R Douce
Journal:  J Cell Biol       Date:  1996-06       Impact factor: 10.539
  4 in total

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