Channa de Silva1, Aparna Mukherjee1, Kana Ram Jat1, Rakesh Lodha1, Sushil Kumar Kabra2. 1. Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India. 2. Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India. skkabra@hotmail.com.
Abstract
OBJECTIVE: To describe etiology, clinical profile, treatment and outcome of children with pulmonary hemorrhage. METHODS: A chart review of children with pulmonary hemorrhage attending Pediatric Pulmonology services of a tertiary care hospital in North-India was done. RESULTS: Data of 44 children (mean age 59.2 ± 32.1 mo; 28 boys) were included for the study. Possible idiopathic pulmonary hemosiderosis 16 (36.4%), post infectious complications 11 (25%), immune mediated disorders 8 (18.2%), cardiac and vascular disorders 7 (15.9%), and airway pathologies 2 (4.5%) were the etiologies of pulmonary hemorrhage. Treatment options like medications, bronchial artery embolization and surgical resections were offered according to the etiology. Children with idiopathic pulmonary hemosiderosis and those with immune mediated diseases were treated with systemic steroids and steroid sparing agents; the latter group took longer time to respond and had more relapses. CONCLUSIONS: Identification of main etiological categories of pulmonary hemorrhage in children could be useful to plan investigations and management of wide range of causes in more practical way.
OBJECTIVE: To describe etiology, clinical profile, treatment and outcome of children with pulmonary hemorrhage. METHODS: A chart review of children with pulmonary hemorrhage attending Pediatric Pulmonology services of a tertiary care hospital in North-India was done. RESULTS: Data of 44 children (mean age 59.2 ± 32.1 mo; 28 boys) were included for the study. Possible idiopathic pulmonary hemosiderosis 16 (36.4%), post infectious complications 11 (25%), immune mediated disorders 8 (18.2%), cardiac and vascular disorders 7 (15.9%), and airway pathologies 2 (4.5%) were the etiologies of pulmonary hemorrhage. Treatment options like medications, bronchial artery embolization and surgical resections were offered according to the etiology. Children with idiopathic pulmonary hemosiderosis and those with immune mediated diseases were treated with systemic steroids and steroid sparing agents; the latter group took longer time to respond and had more relapses. CONCLUSIONS: Identification of main etiological categories of pulmonary hemorrhage in children could be useful to plan investigations and management of wide range of causes in more practical way.
Authors: Nicolas de Prost; Antoine Parrot; Elise Cuquemelle; Clément Picard; Martine Antoine; Joceline Fleury-Feith; Charles Mayaud; Jean-Jacques Boffa; Muriel Fartoukh; Jacques Cadranel Journal: Respir Med Date: 2012-04-25 Impact factor: 3.415
Authors: Chana I C Chin; Shirleen Loloyan Kohn; Thomas G Keens; Monique F Margetis; Roberta M Kato Journal: Orphanet J Rare Dis Date: 2015-08-20 Impact factor: 4.303