Zeynep Selen Karalok1, Birce Dilge Taskin2, Zeliha Brohi Yanginlar2, Esra Gurkas2, Alev Guven2, Aydan Degerliyurt2, Ece Unlu3, Gulsen Kose4. 1. Department of Pediatric Neurology, Ankara Children's Hematology-Oncology Training and Research Hospital, 06110, Dıskapı/Ankara, Turkey. selen_z@yahoo.com. 2. Department of Pediatric Neurology, Ankara Children's Hematology-Oncology Training and Research Hospital, 06110, Dıskapı/Ankara, Turkey. 3. Department of Physical Medicine and Rehabilitation, Ministry of Health Diskapi Yildirim Beyazit Education and Research Hospital, Ankara, Turkey. 4. Department of Pediatric Neurology, Sisli Hamidiye Etfal Research and Training Hospital, Istanbul, Turkey.
Abstract
OBJECTIVE: This study reviews the clinical features, subtypes, and outcomes of childhood Guillain-Barré syndrome (GBS). METHODS: Fifty-four children who attended a tertiary care training and research hospital in Turkey were enrolled in the study. RESULTS: The mean age was 6.5 ± 4.2 years and 32 patients (59.5%) were male. The most common subtype of GBS was acute inflammatory demyelinating polyneuropathy (AIDP), which was seen in 27 patients (50%). Having antecedent history, especially upper respiratory tract infection was significantly more common in AIDP (P = 0.028). Sensorial symptoms were significantly more frequent in axonal type GBS (P = 0.001). When we compare the demyelinating and axonal forms, all of the groups had favorable outcome. CONCLUSION: The diagnosis of pediatric GBS can be delayed because of its variable presentation. Early admission to hospital and early treatment are important for decreasing the need for respiratory support and improving the outcome.
OBJECTIVE: This study reviews the clinical features, subtypes, and outcomes of childhood Guillain-Barré syndrome (GBS). METHODS: Fifty-four children who attended a tertiary care training and research hospital in Turkey were enrolled in the study. RESULTS: The mean age was 6.5 ± 4.2 years and 32 patients (59.5%) were male. The most common subtype of GBS was acute inflammatory demyelinating polyneuropathy (AIDP), which was seen in 27 patients (50%). Having antecedent history, especially upper respiratory tract infection was significantly more common in AIDP (P = 0.028). Sensorial symptoms were significantly more frequent in axonal type GBS (P = 0.001). When we compare the demyelinating and axonal forms, all of the groups had favorable outcome. CONCLUSION: The diagnosis of pediatric GBS can be delayed because of its variable presentation. Early admission to hospital and early treatment are important for decreasing the need for respiratory support and improving the outcome.
Entities:
Keywords:
Childhood GBS; Early treatment; Outcome; Subtypes
Authors: I Nachamkin; P Arzarte Barbosa; P Arzate Barbosa; Huong Ung; H Ung; C Lobato; A Gonzalez Rivera; A Gonzalez Rivera; P Rodriguez; A Garcia Briseno; A Garcia Briseno; L Maria Cordero; L Garcia Perea; L Garcia Perea; J Carlos Perez; M Ribera; P Chico Aldama; G Dávila Guitérrez; L Flores Sarnat; M Ruiz García; J Veitch; C Fitzgerald; D R Cornblath; D Cornblath; M Rodriguez Pinto; M Rodriguez Pinto; J W Griffin; H J Willison; A K Asbury; G M McKhann Journal: Neurology Date: 2007-09-26 Impact factor: 9.910