Literature DB >> 29947369

Chiral modulation of amyloid beta fibrillation and cytotoxicity by enantiomeric carbon dots.

Ravit Malishev1, Elad Arad, Susanta Kumar Bhunia, Shira Shaham-Niv, Sofiya Kolusheva, Ehud Gazit, Raz Jelinek.   

Abstract

Enantiomeric carbon dots (C-dots) synthesized from l-lysine or d-lysine, modulate aggregation and cytotoxicity of amyloid beta-42 (Aβ42), the primary constituent of the amyloid plaques associated with Alzheimer's disease. In particular, l-Lys-C-dots dramatically remodeled Aβ42 secondary structure and fibril morphologies, as well as inhibited Aβ42 cytotoxicity and membrane interactions.

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Year:  2018        PMID： 29947369     DOI： 10.1039/c8cc03235a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

Review 1.  You Don't Learn That in School: An Updated Practical Guide to Carbon Quantum Dots.

Authors:  Helena B A Sousa; Catarina S M Martins; João A V Prior
Journal:  Nanomaterials (Basel)       Date:  2021-03-01       Impact factor: 5.076

2.  Mitigating Human IAPP Amyloidogenesis In Vivo with Chiral Silica Nanoribbons.

Authors:  Ava Faridi; Yunxiang Sun; Yutaka Okazaki; Guotao Peng; Jie Gao; Aleksandr Kakinen; Pouya Faridi; Mei Zhao; Ibrahim Javed; Anthony W Purcell; Thomas P Davis; Sijie Lin; Reiko Oda; Feng Ding; Pu Chun Ke
Journal:  Small       Date:  2018-10-07       Impact factor: 13.281

Review 3.  Half a century of amyloids: past, present and future.

Authors:  Pu Chun Ke; Ruhong Zhou; Louise C Serpell; Roland Riek; Tuomas P J Knowles; Hilal A Lashuel; Ehud Gazit; Ian W Hamley; Thomas P Davis; Marcus Fändrich; Daniel Erik Otzen; Matthew R Chapman; Christopher M Dobson; David S Eisenberg; Raffaele Mezzenga
Journal:  Chem Soc Rev       Date:  2020-07-07       Impact factor: 54.564

Review 4.  Understanding and controlling amyloid aggregation with chirality.

Authors:  Alejandro R Foley; Jevgenij A Raskatov
Journal:  Curr Opin Chem Biol       Date:  2021-02-18       Impact factor: 8.972

5.  α-synuclein interaction with zero-valent iron nanoparticles accelerates structural rearrangement into amyloid-susceptible structure with increased cytotoxic tendency.

Authors:  Seyedeh Sahar Tahaei Gilan; Dorsa Yahya Rayat; Twana Ahmed Mustafa; Falah Mohammad Aziz; Koorosh Shahpasand; Keivan Akhtari; Abbas Salihi; Osama K Abou-Zied; Mojtaba Falahati
Journal:  Int J Nanomedicine       Date:  2019-06-27

6.  Investigation on the chirality mechanism of chiral carbon quantum dots derived from tryptophan.

Authors:  Yingying Wei; Lin Chen; Junli Wang; Xuguang Liu; Yongzhen Yang; Shiping Yu
Journal:  RSC Adv       Date:  2019-01-25       Impact factor: 3.361

7.  Tyrosine carbon dots inhibit fibrillation and toxicity of the human islet amyloid polypeptide.

Authors:  Daniel Nir Bloch; Shani Ben Zichri; Sofiya Kolusheva; Raz Jelinek
Journal:  Nanoscale Adv       Date:  2020-11-10

8.  Chiral Interface of Amyloid Beta (Aβ): Relevance to Protein Aging, Aggregation and Neurodegeneration.

Authors:  Victor V Dyakin; Thomas M Wisniewski; Abel Lajtha
Journal:  Symmetry (Basel)       Date:  2020-04-07       Impact factor: 2.713
  8 in total

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