Literature DB >> 29947292

"Why did I get that part of you?" Understanding addiction genetics through family history.

Molly J Dingel1, Jenny Ostergren2, Barbara A Koenig3, Jennifer McCormick4.   

Abstract

Scientists have sought to uncover the genetic bases of many diseases and disorders. In response, scholars defined "geneticization" to describe genetic infiltration of understandings of health and illness. In our research, we interviewed 63 individuals in addiction treatment programs to identify what form of geneticization best fits individuals' description of their own addiction. Individuals' narratives of their lives, which include family history and are influenced by cultural and structural factors, affect respondents' reactions to a potential genetic basis of addiction. Most who had a family history of addiction subscribed to a notion that addiction "runs in families," while most who lacked a family history of addiction used this fact to reject the notion of genetic inheritance of addiction. We conclude that though we see elements of several different versions of geneticization, Nikolas Rose's version, that genetics affects peoples' perceptions of addiction in small but important ways, best describes our respondents' views.

Entities:  

Keywords:  addiction; behavioral genetics; substance use

Mesh:

Year:  2018        PMID: 29947292      PMCID: PMC6342673          DOI: 10.1177/0963662518785350

Source DB:  PubMed          Journal:  Public Underst Sci        ISSN: 0963-6625


  38 in total

1.  Stigmatization of people with mental illnesses: a follow-up study within the Changing Minds campaign of the Royal College of Psychiatrists.

Authors:  Arthur Crisp; Michael Gelder; Eileen Goddard; Howard Meltzer
Journal:  World Psychiatry       Date:  2005-06       Impact factor: 49.548

2.  Keeping it together: how women use the biomedical explanatory model to manage the stigma of depression.

Authors:  Rita Schreiber; Gwen Hartrick
Journal:  Issues Ment Health Nurs       Date:  2002-03       Impact factor: 1.835

3.  The experience of addiction as told by the addicted: incorporating biological understandings into self-story.

Authors:  Rachel R Hammer; Molly J Dingel; Jenny E Ostergren; Katherine E Nowakowski; Barbara A Koenig
Journal:  Cult Med Psychiatry       Date:  2012-12

Review 4.  A brief history of research on the genetics of alcohol and other drug use disorders.

Authors:  Marc A Schuckit
Journal:  J Stud Alcohol Drugs Suppl       Date:  2014

Review 5.  After geneticization.

Authors:  Michael Arribas-Ayllon
Journal:  Soc Sci Med       Date:  2016-05-07       Impact factor: 4.634

6.  Postgenomics, uncertain futures, and the familiarization of susceptibility genes.

Authors:  Gillian Chilibeck; Margaret Lock; Megha Sehdev
Journal:  Soc Sci Med       Date:  2010-05-08       Impact factor: 4.634

7.  "A disease like any other"? A decade of change in public reactions to schizophrenia, depression, and alcohol dependence.

Authors:  Bernice A Pescosolido; Jack K Martin; J Scott Long; Tait R Medina; Jo C Phelan; Bruce G Link
Journal:  Am J Psychiatry       Date:  2010-09-15       Impact factor: 18.112

8.  Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Authors:  Thorgeir E Thorgeirsson; Daniel F Gudbjartsson; Ida Surakka; Jacqueline M Vink; Najaf Amin; Frank Geller; Patrick Sulem; Thorunn Rafnar; Tõnu Esko; Stefan Walter; Christian Gieger; Rajesh Rawal; Massimo Mangino; Inga Prokopenko; Reedik Mägi; Kaisu Keskitalo; Iris H Gudjonsdottir; Solveig Gretarsdottir; Hreinn Stefansson; John R Thompson; Yurii S Aulchenko; Mari Nelis; Katja K Aben; Martin den Heijer; Asger Dirksen; Haseem Ashraf; Nicole Soranzo; Ana M Valdes; Claire Steves; André G Uitterlinden; Albert Hofman; Anke Tönjes; Peter Kovacs; Jouke Jan Hottenga; Gonneke Willemsen; Nicole Vogelzangs; Angela Döring; Norbert Dahmen; Barbara Nitz; Michele L Pergadia; Berta Saez; Veronica De Diego; Victoria Lezcano; Maria D Garcia-Prats; Samuli Ripatti; Markus Perola; Johannes Kettunen; Anna-Liisa Hartikainen; Anneli Pouta; Jaana Laitinen; Matti Isohanni; Shen Huei-Yi; Maxine Allen; Maria Krestyaninova; Alistair S Hall; Gregory T Jones; Andre M van Rij; Thomas Mueller; Benjamin Dieplinger; Meinhard Haltmayer; Steinn Jonsson; Stefan E Matthiasson; Hogni Oskarsson; Thorarinn Tyrfingsson; Lambertus A Kiemeney; Jose I Mayordomo; Jes S Lindholt; Jesper Holst Pedersen; Wilbur A Franklin; Holly Wolf; Grant W Montgomery; Andrew C Heath; Nicholas G Martin; Pamela A F Madden; Ina Giegling; Dan Rujescu; Marjo-Riitta Järvelin; Veikko Salomaa; Michael Stumvoll; Tim D Spector; H-Erich Wichmann; Andres Metspalu; Nilesh J Samani; Brenda W Penninx; Ben A Oostra; Dorret I Boomsma; Henning Tiemeier; Cornelia M van Duijn; Jaakko Kaprio; Jeffrey R Gulcher; Mark I McCarthy; Leena Peltonen; Unnur Thorsteinsdottir; Kari Stefansson
Journal:  Nat Genet       Date:  2010-04-25       Impact factor: 38.330

9.  "I don't have to know why it snows, I just have to shovel it!": Addiction Recovery, Genetic Frameworks, and Biological Citizenship.

Authors:  Molly J Dingel; Jenny Ostergren; Kathleen Heaney; Barbara A Koenig; Jennifer McCormick
Journal:  Biosocieties       Date:  2017-07-11

10.  Associations of the 5-hydroxytryptamine (serotonin) receptor 1B gene (HTR1B) with alcohol, cocaine, and heroin abuse.

Authors:  Jian Cao; Emily LaRocque; Dawei Li
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2013-01-17       Impact factor: 3.568

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